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EMAGE:628

Msx1 homeobox, msh-like 1 ( MGI:97168)
TS14 (17 Somite no.)
in situ hybridisation

Data Images
EMAGE:628

Expression pattern clarity: two stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Expression Pattern Description
Spatial Annotation:
EMAGE:628Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
628_wholemount_strong_3D_1.wlz
628_wholemount_moderate_3D_1.wlz
628_wholemount_notDetected_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:628_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: two stars
Text Annotation:
StructureLevelPatternNotes
1st branchial arch mesenchyme derived from neural crest
strong strong
regional
2nd branchial arch mesenchyme derived from neural crest
strong strong
regional
neural tube roof plate
strong strong
Extends along entire axis and into anterior of posterior neuropore but not in the most posterior of the neuropore.
forelimb bud
strong strong
Unknown which cell type expresses
mesenchyme derived from lateral plate
strong strong
regionalExpressed in lateral mesoderm
future midbrain roof plate
strong strong
Extends along entire axis and into anterior of posterior neuropore but not in the most posterior of the neuropore.
rhombomere 08 roof plate
strong strong
Extends along entire axis and into anterior of posterior neuropore but not in the most posterior of the neuropore.
rhombomere 02 roof plate
strong strong
Extends along entire axis and into anterior of posterior neuropore but not in the most posterior of the neuropore.
rhombomere 03 roof plate
strong strong
Extends along entire axis and into anterior of posterior neuropore but not in the most posterior of the neuropore.
rhombomere 04 roof plate
strong strong
Extends along entire axis and into anterior of posterior neuropore but not in the most posterior of the neuropore.
rhombomere 05 roof plate
strong strong
Extends along entire axis and into anterior of posterior neuropore but not in the most posterior of the neuropore.
rhombomere 06 roof plate
strong strong
Extends along entire axis and into anterior of posterior neuropore but not in the most posterior of the neuropore.
rhombomere 07 roof plate
strong strong
Extends along entire axis and into anterior of posterior neuropore but not in the most posterior of the neuropore.
rhombomere 01 roof plate
strong strong
Extends along entire axis and into anterior of posterior neuropore but not in the most posterior of the neuropore.
prosencephalon roof plate
strong strong
Extends along entire axis and into anterior of posterior neuropore but not in the most posterior of the neuropore.
future diencephalon roof plate
strong strong
Extends along entire axis and into anterior of posterior neuropore but not in the most posterior of the neuropore.
caudal neuropore
strong strong
regionalExpressed only in anterior of the neuropore. Expression is not detected in the posterior of the neuropore.
extraembryonic component
strong strong
Expression at base of allantois
head mesenchyme derived from neural crest
moderate moderate
Annotation Validation: submitter
Detection Reagent
Type:in situ hybridisation probe
Identifier:MGI:14954
Entity Detected:Msx1, homeobox, msh-like 1 ( MGI:97168)
Sequence:sense strand is shown

>MGI:14954
GGAACCCAGGAGCTCGCAGAAGCCGGTCAGGAGCTCGCAGAAGCCGGTCGCGCTCCCAGCCTGCCCGAAA
CCCATGATCCAGGGCTGTCTCGAGCTGCGGCTGGAGGGGGGGTCCGGCTCTGCATGGCCCCGGCTGCTGC
TATGACTTCTTTGCCACTCGGTGTCAAAGTGGAGGACTCCGCCTTCGCCAAGCCTGCTGGGGGAGGCGTT
GGCCAAGCCCCCGGGGCTGCTGCGGCCACCGCAACCGCCATGGGCACAGATGAGGAGGGGGCCAAGCCCA
AAGTGCCCGCTTCACTCCTGCCCTTCAGCGTGGAGGCCCTCATGGCCGATCACAGGAAGCCCGGGGCCAA
GGAGAGCGTCCTGGTGGCCTCCGAAGGGGCTCAGGCAGCGGGTGGCTCGGTGCAGCACTTGGGCACCCGG
CCCGGGTCTCTGGGCGCCCCGGATGCGCCCTCCTCGCCGCGGCCTCTCGGCCATTTCTCAGTCGGAGGAC
TCCTCAAGCTGCCAGAAGATGCTCTGGTGAAGGCCGAAAGCCCCGAGAAACTAGATCGGACCCCGTGGAT
GCAGAGTCCCCGCTTCTCCCCGCCCCCAGCCAGACGGCTGAGTCCCCCAGCATGCACCCTACGCAAGCAC
AAGACCAACCGCAAGCCCAGGACGCCTTTCACCACAGCTCAGCTGCTGGCTCTGGAGCGCAAGTTCCGCC
AGAAGCAGTACCTGTCTATTGCCGAGCGCGCGGAATTCTCCAGCTCGCTCAGCCTCACCGAGACCCAGGT
GAAGATCTGGTTCCAGAACCGTCGCGCTAAGGCCAAGAGACTGCAGGAGGCGGAGCTGGAGAAGCTGAAG
ATGGCCGCGAAACCCATGTTGCCGCCTGCTGCCTTCGCTCTCTTTTCCTCTTGGCGGTCCTGCAGCGGTG
GCTGCAGCTGCGGGCGCCTCACTCTACAGTGCCTCTGGCCCTTTCCAGCGCGCCGCGCTGCCTGTAGCGC
CCGTGGGACTCTACACCGCCCATGTAGGCTACAGCATGTACCACCTGACTTAGGTGGGTCCAGAGTCACC
TCCCTGTGGTGCCATCCCCTCCCCAGCCACCTCTTTGAGCAGAGCAGCGGGAGTCCTTCCTAGGAAGCTC
TGCTGCCCTATACCACCTGGTCCCTTCTCTTAAACCCCTTGCTACACACTTCCTCCTGGTTGTCGCTTCC
TAAACCTTCCTCATCTGACCCCTTCTGGGAAGAAAAAGAATTGGTCGGAAGATGTTCAGGTTTTTCGAGT
TTTTTCTAGATTTACATGCGCAAGTTATAAAATGTGGAAACTAAGGATGCAGAGGCCAAGAGATTTATCC
GTGGTCCCCAGCAGAATTAGAGGCTGAAGGAGACCAGAGGCCAAAAGGACTAGAGGCCATGAGACTCCAT
CAGCTGCTTCCGGTCCTGAAACCAGGCAGGACTTGCACAGAGAAATTGCTAAGCTAATCGGTGCTCCAAG
AGATGAGCCCAGCCCTATAGAAAGCAAGAGCCCAGCTCCTTCCACTGTCAAACTCTAAGCGCTTTGGCAG
CAAAGCATTGCTCTGAGGGGGCAGGGCGCATGCTGCTGCTTCACCAAGGTAGGTTAAAGAGACTTTCCCA
GGACCAGAAAAAAAGAAGTAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAACAAATCTGTTCTATTAACAG
TACATTTTCGTGGCTCTCAAGCATCCCTTTTGAAGGGACTGGTGTGTACTATGTAATATACTGTATATTT
GAAATTTTATTATCATTTATATTATAGCTATATTTGTTAAATAAATTAATTTTAAGCTAC
nt 1 - nt 1810 of X14759.1
Notes:Probe is the ~2kb Msx1 (Hox-7.1) cDNA originally described by Hill et al., 1989 [PMID:2565278] .
Chemistry:RNA
Strand:antisense
Label:digoxigenin
Specimen
Organism:mouse
Age:17 Somite no.
Theiler Stage:TS14
Mutations:none (wild-type)
Preparation:wholemount
Procedures
Fixation:4% paraformaldehyde
Staining procedure:alkaline phosphatase + NBT/BCIP
General Information
Principal investigator:Ruth Arkell, MRC Mammalian Genetics Unit, null, Harwell, UK OX11 ORD
Submitted by:Ruth Arkell, MRC Mammalian Genetics Unit, null, Harwell, UK OX11 ORD
Experiment type:non-screen
References:[ doi:10.1101/gad.3.1.26] [ PMID:2565278] Hill RE, Jones PF, Rees AR, Sime CM, Justice MJ, Copeland NG, Jenkins NA, Graham E, Davidson DR 1989 A new family of mouse homeo box-containing genes: molecular structure, chromosomal location, and developmental expression of Hox-7.1. Genes Dev (3):26-37
Links:MGI:14954 same probe
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceEMAGE