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EMAGE:645

Msx1 homeobox, msh-like 1 ( MGI:97168)
TS20 (12.5 dpc)
in situ hybridisation

Data Images
EMAGE:645 EMAGE:645
Fig 4B, Mackenzie et al , 1991 [PMID:1680043] . Copyright: This image is from Development and is displayed with the permission of the Company of Biologists Ltd who owns the copyright. Fig 4A, Mackenzie et al , 1991 [PMID:1680043] . Copyright: This image is from Development and is displayed with the permission of the Company of Biologists Ltd who owns the copyright.

Expression pattern clarity: three stars
Find spatially similar expression patterns: Find spatially similar patterns
Notes:
Roughly equivalent bright- and dark-field sections are shown below. Image annotations: d, dorsal midline of neural tube; t, telencephalon; cp, lateral choroid plexus. Scale bar, 0.5mm
Expression Pattern Description
Spatial Annotation:
EMAGE:645EMAGE:645Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
3D mapping3D context movie

View mapped 3D expression image EMAGE genex expression entry
Download individual expression domains:
645_voxel_strong_3D_1.wlz
645_voxel_moderate_3D_1.wlz
645_voxel_notDetected_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:645_all_domains.zip
Find spatially similar expression patterns: EMAGE spatially similar patterns
Morphological match to the template: two stars
Text Annotation:
StructureLevelPatternNotes
choroid invagination
detected detected
regionalExpression in the thinning epithelium destined to become the lateral choroid plexus
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:MGI:12837
Entity Detected:Msx1, homeobox, msh-like 1 ( MGI:97168)
Notes:The Msx1 (Hox-7) probe used in this study by Mackenzie et al, 1991 [PMID:1685989] is defined as a "600bp EcoRI fragment from one cDNA clone, containing 375bp of protein coding sequence (Mackenzie et al , 1991 [PMID:1680043] ). Mackenzie et al , 1991 [PMID:1680043] depict the probe schematically in Fig 1. Exact end positions are unknown as these values are ambiguous when comparing to Msx1 cDNA sequences in GenBank (eg. NM_010835.1).
Chemistry:RNA
Strand:antisense
Label:S35
Specimen
Organism:mouse
Strain:Manchester
Age:12.5 dpc
Theiler Stage:TS20
Mutations:none (wild-type)
Preparation:section
Procedures
Staining procedure:autoradiography
General Information
Authors:Mackenzie et al, 1991 [PMID:1685989] Indexed by GXD, Spatially mapped by EMAGE
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ PMID:1685989] MacKenzie A, Ferguson MW, Sharpe PT 1991 Hox-7 expression during murine craniofacial development. Development (0):601-11
 [ PMID:1680043] Mackenzie A, Leeming GL, Jowett AK, Ferguson MW, Sharpe PT 1991 The homeobox gene Hox 7.1 has specific regional and temporal expression patterns during early murine craniofacial embryogenesis, especially tooth development in vivo and in vitro. Development (0):269-85
Links:MGI:2158936 same experiment
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceMGI