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EMAGE:653

Msx1 homeobox, msh-like 1 ( MGI:97168)
TS18 (10.5 dpc)
in situ hybridisation

Data Images
EMAGE:653 EMAGE:653 EMAGE:653 EMAGE:653
Fig2A Mackenzie et al , 1991 [PMID:1680043] . Copyright: This image is from Development and is displayed with the permission of the Company of Biologists Ltd who owns the copyright. Fig2B Mackenzie et al , 1991 [PMID:1680043] . Copyright: This image is from Development and is displayed with the permission of the Company of Biologists Ltd who owns the copyright. Fig2C Mackenzie et al , 1991 [PMID:1680043] . Copyright: This image is from Development and is displayed with the permission of the Company of Biologists Ltd who owns the copyright. Fig2D Mackenzie et al , 1991 [PMID:1680043] . Copyright: This image is from Development and is displayed with the permission of the Company of Biologists Ltd who owns the copyright.

Expression pattern clarity: three stars
Find spatially similar expression patterns: Find spatially similar patterns
Notes:
B,C, and D are enlargements of A showing the mandibular, maxillary, and fronto-nasal processes respectively. Image annotations: L, lateral nasal; MX, maxillary process; M, mandibular process; ; H, heart; P, pericardium; B, brain.
Expression Pattern Description
Spatial Annotation:
EMAGE:653EMAGE:653Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
3D mapping3D context movie

View mapped 3D expression image EMAGE genex expression entry
Download individual expression domains:
653_voxel_strong_3D_1.wlz
653_voxel_moderate_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:653_all_domains.zip
Find spatially similar expression patterns: EMAGE spatially similar patterns
Morphological match to the template: three stars
Text Annotation:
StructureLevelPatternNotes
brain
detected detected
Expression in the brain meninges
medial-nasal process
strong strong
regional
heart
detected detected
Expression in the heart and pericardium
1st branchial arch mandibular component mesenchyme
strong strong
regionalIntense labeling anteriorly throughout the mesenchyme that leveled off in the middle third and the posterior third was barely above background. More intense labeling in the top (oral) half.
1st branchial arch maxillary component mesenchyme
strong strong
regional
latero-nasal process
strong strong
regional
tongue
detected detected
regionalExpression in the mesenchyme of the anterior component of the tongue anlage
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:MGI:12837
Entity Detected:Msx1, homeobox, msh-like 1 ( MGI:97168)
Notes:The probe used in this study by Mackenzie et al , 1991 [PMID:1680043] is depicted in Fig 1 of that paper and described as a "600bp EcoRI fragment", "containing 375bp of coding sequence". Exact end positions are unknown as these values are ambiguous when comparing to other Msx1 cDNA sequences (eg. NM_010835.1)
Chemistry:RNA
Strand:antisense
Label:unspecified radioactivity
Specimen
Organism:mouse
Strain:Manchester
Age:10.5 dpc
Theiler Stage:TS18
Mutations:none (wild-type)
Preparation:section
Procedures
Fixation:paraformaldehyde
Staining procedure:autoradiography
General Information
Authors:Mackenzie et al , 1991 [PMID:1680043] Indexed by GXD, Spatially mapped by EMAGE
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ PMID:1680043] Mackenzie A, Leeming GL, Jowett AK, Ferguson MW, Sharpe PT 1991 The homeobox gene Hox 7.1 has specific regional and temporal expression patterns during early murine craniofacial embryogenesis, especially tooth development in vivo and in vitro. Development (0):269-85
Links:MGI:2136379 same experiment
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceMGI