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EMAGE:686

Nodal nodal ( MGI:97359)
TS11 (7.5 dpc)
in situ hybridisation

Data Images
EMAGE:686
Fig 5e, Norris et al, 2002 [PMID:12091315] . Copyright: This image is from Development and is displayed with the permission of the Company of Biologists Ltd who owns the copyright.

Expression pattern clarity: three stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Notes:
Image annotation: n - node.
Expression Pattern Description
Spatial Annotation:
EMAGE:686Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
686_wholemount_strong_3D_1.wlz
686_wholemount_notDetected_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:686_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: two stars
Text Annotation:
StructureLevelPatternNotes
node
detected detected
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:MGI:1335832
Entity Detected:Nodal, nodal ( MGI:97359)
Notes:The nodal probe used in this study by Norris et al, 2002 [PMID:12091315] is described as that used by Conlon et al, 1994 [PMID:7924997] ie "nucleotides 330-660, cloned into pBluescript KS-II, and transcribed from the T3 promoter". End positions are unknown as these nucleotide positions are not referred to a specific clone.
Chemistry:RNA
Strand:antisense
Specimen
Organism:mouse
Strain:ICR
Age:7.5 dpc
Theiler Stage:TS11
Mutations:none (wild-type)
Preparation:wholemount
Procedures
General Information
Authors:Norris et al, 2002 [PMID:12091315] Indexed by GXD, Spatially mapped by EMAGE
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ PMID:12091315] Norris DP, Brennan J, Bikoff EK, Robertson EJ 2002 The Foxh1-dependent autoregulatory enhancer controls the level of Nodal signals in the mouse embryo. Development (129):3455-68
 [ PMID:7924997] Conlon FL, Lyons KM, Takaesu N, Barth KS, Kispert A, Herrmann B, Robertson EJ 1994 A primary requirement for nodal in the formation and maintenance of the primitive streak in the mouse. Development (120):1919-28
Links:MGI:2183524 same experiment
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceMGI