EMAGE mouse gene expression spatial database

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EMAGE:712

Neurog2 neurogenin 2 ( MGI:109619)
TS20 (12.5 dpc)
in situ hybridisation

Data Images


Fig 6A Corbin et al, 2003 [PMID:12930780] . Copyright: This image is from Development and is displayed with the permission of the Company of Biologists Ltd who owns the copyright.

Expression pattern clarity:
Find spatially similar expression patterns:

Notes:

Image annotations: MGE -medial ganglionic eminence; LGE - lateral ganglionic eminence. Arrow shows the ventral-most limit of expression.

Expression Pattern Description

Spatial Annotation:

Annotation colour key:

	strong
	moderate
	weak
	possible
	not detected

3D mapping

3D context movie

View mapped 3D expression image

Download individual expression domains:

712_voxel_strong_3D_1.wlz

712_voxel_moderate_3D_1.wlz

712_voxel_notDetected_3D_1.wlz

(what is wlz format?)

Download all expression domains:

EMAGE:712_all_domains.zip

Find spatially similar expression patterns:

Morphological match to the template:

Text Annotation:

Structure

Level

Pattern

Notes

telencephalon

detected

regional

Expression normally extends just across the cortical sulcus into the dorsal lateral ganglionic eminence.

Annotation Validation:

EMAGE Editor

Detection Reagent

Type:	in situ hybridisation probe
Identifier:	MGI:2676164
Entity Detected:	Neurog2, neurogenin 2 ( MGI:109619)
Sequence:	sense strand is shown >MGI:2676164 CGTGCTCGGTTCCGGGCTGCGGGGACATTCCCGGACACACACCGGAGCAGCAGCTGCGCCGCGACACATC TGGAGCCGCGTAGGATGTTCGTCAAATCTGAGACTCTGGAGTTGAAGGAGGAAGAGGAGGTACTGATGCT GCTGGGCTCGGCTTCCCCGGCCTCGGCGACCCTGACCCCGATGTCCTCCAGCGCGGACGAGGAGGAGGAC GAGGAGCTGCGCCGGCCGGGCTCCGCGCGTGGGCAGCGTGGAGCGGAAGCCGGGCAGGGGGTGCAGGGCA GTCCGGCGTCGGGTGCCGGGGGTTGCCGGCCAGGGCGGCTGCTGGGCCTGATGCACGAGTGCAAGCGTCG CCCGTCGCGCTCACGGGCCGTCTCCCGAGGTGCCAAGACGGCGGAGACGGTGCAGCGCATCAAGAAGACC CGCAGGCTCAAGGCCAACAACCGCGAGCGCAACCGCATGCACAACCTAAACGCCGCGCTGGACGCGCTGC GCGAGGTGCTGCCCACCTTCCCCGAGGATGCCAAGCTCACGAAGATCGAGACGCTGCGCTTCGCCCACAA TTACATCTGGGCGCTCACCGAGACTCTGCGCCTGGCGGACCACTGCGCCGGCGCCGGTGGCCTCCAGGGG GCGCTCTTCACGGAGGCGGTGCTCCTGAGCCCGGGAGCTGCGCTCGGCGCCAGCGGGGACAGCCCTTCTC CACCTTCCTCCTGGAGCTGCACCAACAGCCCGGCGTCATCCTCCAACTCCACGTCCCCATACAGCTGCAC TTTATCGCCCGCTAGCCCCGGGTCAGACGTGGACTACTGGCAGCCCCCACCTCCGGAGAAGCATCGTTAT GCGCCTCACCTGCCCCTCGCCAGGGACTGTATCTAGAGCTGCGGGTCTCCCTCTCTCGTCCTCTACCCGG CCCTCTTCCCATCCTTCTCCCGCCCCTCACCCTCCACGCCCCGGACTCCACTTCACAGAGCAGAGGTGGC CCTTGCAATCCCCTCGGCGGCTGGTGCATTCGGGGGTGGAGACCAGCTCTGGTTTATTGAAGATGTGAGG ATTTATGGTCAAAGAGGACTATGGCGTGTGGGAGTGGGGGCTGGCGTGGGGAACCTCGTAAGACTGTAAA AGACACTGAGAAAAAGTACCATAACTAACGAGTGTGCAGAGCAGACTGACGCTCCTCCCCTCTCTCAGAG CTGCTGGAGGAGAACTCCGGGCAGGCAGTTCGTGTGAATCTCTCAGAGGGAATGCAACTGGTCCCTGTGA TCTTTTCACCTTCGTTTCTACATAGAGATGTTAATGTCAGTCGAAAGAAATGTATTTTAGCATCTGAATG AATTTACTGGTAATAATATTATCCACACATTTGCAATGGCTGGCATCTGCTCTATTCCCATTGCTGTCTG CAGGCTGTGGGA
	nt 1 - nt 1412 of Y07621.1
Notes:	The Neurog2 (Ngn2, Math4A) probe used in this study by Corbin et al, 2003 [PMID:12930780] is described as that used by Gradwohl et al, 1996 [PMID:8948587] ie a "1.4-kb full-length cDNA" which is shown in Fig1A therein and was deposited in GenBank as Y07621.
Chemistry:	RNA
Strand:	antisense
Label:	digoxigenin

Specimen

Organism:	mouse
Age:	12.5 dpc
Theiler Stage:	TS20
Mutations:	none (wild-type)
Preparation:	section

Procedures

Fixation:	4% paraformaldehyde
Embedding:	cryosection

General Information

Authors:	Corbin et al, 2003 [PMID:12930780] Indexed by GXD, Spatially mapped by EMAGE
Submitted by:	EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:	non-screen
References:	[ doi:10.1242/dev.00717] [ PMID:12930780] Corbin JG, Rutlin M, Gaiano N, Fishell G 2003 Combinatorial function of the homeodomain proteins Nkx2.1 and Gsh2 in ventral telencephalic patterning. Development (130):4895-906
	[ doi:10.1006/dbio.1996.0297] [ PMID:8948587] Gradwohl G, Fode C, Guillemot F 1996 Restricted expression of a novel murine atonal-related bHLH protein in undifferentiated neural precursors. Dev Biol (180):227-41
Links:	MGI:2676246 same experiment
	Ensembl same gene
	Allen Brain Atlas same gene
	BioGPS same gene
	International Mouse Knockout Project Status same gene
	GEISHA Chicken ISH Database same gene
	EMBL-EBI Gene Expression Atlas same gene
	BrainStars same gene
	ViBrism same gene
Data Source