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EMAGE:75

Gbx2 gastrulation brain homeobox 2 ( MGI:95668)
TS15 (9.5 dpc)
in situ hybridisation

Data Images
EMAGE:75
Figure 3O of Suda et al., 2001 [PMID:11493561] . Copyright: This image is from Development and is displayed with the permission of the Company of Biologists Ltd. who owns the copyright.

Expression pattern clarity: three stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Expression Pattern Description
Spatial Annotation:
EMAGE:75Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
75_wholemount_strong_3D_1.wlz
75_wholemount_moderate_3D_1.wlz
75_wholemount_notDetected_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:75_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: three stars
Text Annotation:
StructureLevelPatternNotes
future midbrain
detected detected
regionalExpression at isthmus.
future hindbrain
detected detected
regionalExpression at isthmus.
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:MGI:20957
Entity Detected:Gbx2, gastrulation brain homeobox 2 ( MGI:95668)
Notes:Probe used in this study by Suda et al., 2001 [PMID:11493561] is indicated as being described by Bulfone et al., 1993 [PMID:7687285] ie. a "0.65 kb fragment derived from the 3' untranslated region of the Gbx-2 cDNA". Probe end positions unspecified.
Chemistry:RNA
Strand:antisense
Label:digoxigenin
Specimen
Organism:mouse
Age:9.5 dpc
Theiler Stage:TS15
Mutations:none (wild-type)
Preparation:wholemount
Procedures
Fixation:4% paraformaldehyde
Staining procedure:undefined
General Information
Authors:Suda et al., 2001 [PMID:11493561] Indexed by GXD, Spatially mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ PMID:11493561] Suda Y, Hossain ZM, Kobayashi C, Hatano O, Yoshida M, Matsuo I, Aizawa S 2001 Emx2 directs the development of diencephalon in cooperation with Otx2. Development (128):2433-50
 [ PMID:7687285] Bulfone A, Puelles L, Porteus MH, Frohman MA, Martin GR, Rubenstein JL 1993 Spatially restricted expression of Dlx-1, Dlx-2 (Tes-1), Gbx-2, and Wnt-3 in the embryonic day 12.5 mouse forebrain defines potential transverse and longitudinal segmental boundaries. J Neurosci (13):3155-72
Links:MGI:2148275 same embryo
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceMGI