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EMAGE:757

Hoxa2 homeobox A2 ( MGI:96174)
TS15 (9.5 dpc)
in situ hybridisation

Data Images
EMAGE:757
Fig 6A Zhang et al., 1994 [PMID:7956823] . Copyright: This image is from Development and is displayed with the permission of The Company of Biologists Ltd. who owns the copyright.

Expression pattern clarity: three stars
Find spatially similar expression patterns: Find spatially similar patterns
Notes:
Abbreviations used: ov, otic vesicle; r1/2, expression at the level of r1/r2 (arrowhead [boundary of rhombomers 1 and 2]).
Expression Pattern Description
Spatial Annotation:
EMAGE:757EMAGE:757Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
3D mapping3D context movie

View mapped 3D expression image EMAGE genex expression entry
Download individual expression domains:
757_voxel_strong_3D_1.wlz
757_voxel_moderate_3D_1.wlz
757_voxel_notDetected_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:757_all_domains.zip
Find spatially similar expression patterns: EMAGE spatially similar patterns
Morphological match to the template: two stars
Text Annotation:
StructureLevelPatternNotes
future hindbrain
strong strong
regionalHoxa2 is detected in hindbrain neuroectoderm with an anterior boundary of expression at the level of r1/r2 boundary.
facio-acoustic vii-viii preganglion complex
detected detected
single cellExpression is detected in neural crest cells of the VII/VIII cranial ganglia (not shown).
3rd branchial arch
detected detected
single cellExpression is detected in neural crest cells within the second and third branchial arches (not shown).
2nd branchial arch
detected detected
single cellExpression is detected in neural crest cells within the second and third branchial arches (not shown).
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:MGI:1345111
Entity Detected:Hoxa2, homeobox A2 ( MGI:96174)
Sequence:sense strand is shown

>MGI:1345111
CCTTCTGGAGAGGGAAGGGTACACTTTTCAGCAAAATGCGCTCTCTCAACAGCAGGCTCCCAATGGACAC
AATGGCGACTCCCAAACTTTCCCAGTTTCGCCTTTAACCAGCAATGAGAAAAATTTGAAACATTTTCAGC
ACCAGTCACCCACTGTTCCTAACTGCTTGTCAACAATGGGCCAGAACTGTGGAGCTGGCCTAAACAATGA
CAGTCCCGAGGCCATCGAGGTCCCCTCTTTGCAGGACTTCAATGTTTTCTCCACAGATTCCTGCCTGCA
nt 901 - nt 1179 of NM_010451.1
Notes:The probe used in this study by Zhang et al., 1994 [PMID:7956823] was "a 280 bp ApaI-PstI fragment of the Hoxa-2 gene".
Chemistry:RNA
Strand:antisense
Label:S35
Specimen
Organism:mouse
Strain:C57BL/6 x CBA
Age:9.5 dpc
Theiler Stage:TS15
Mutations:none (wild-type)
Preparation:section
Procedures
Embedding:paraffin
Staining procedure:autoradiography
General Information
Authors:Zhang et al., 1994 [PMID:7956823] . Indexed by GXD, Spatially mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ PMID:7956823] Zhang M, Kim HJ, Marshall H, Gendron-Maguire M, Lucas DA, Baron A, Gudas LJ, Gridley T, Krumlauf R, Grippo JF 1994 Ectopic Hoxa-1 induces rhombomere transformation in mouse hindbrain. Development (120):2431-42
Links:MGI:1345129 same experiment
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceMGI