Quicksearch Help

(Click the icon to keep this page displayed.)

EMAGE:815

Prrx1 paired related homeobox 1 ( MGI:97712)
TS17 (10.5 dpc)
in situ hybridisation

Data Images
EMAGE:815 EMAGE:815
Figure 10A of Conway et al., 1997 [PMID:9053326] Copyright: This image is from Development and is displayed with the permission of The Company of Biologists Ltd. who owns the copyright. Figure 10B of Conway et al., 1997 [PMID:9053326] Copyright: This image is from Development and is displayed with the permission of The Company of Biologists Ltd. who owns the copyright.

Expression pattern clarity: three stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Notes:
Image B is a higher magnification of the cardiac region of the embryo shown in Image A. Image annotations: M - maxilla; F - fore limb bud; H - hind limb bud; O - cardiac outflow tract; 1,2 - branchial arches 1 and 2; arrows indicate cardiac outflow tract.
Expression Pattern Description
Spatial Annotation:
EMAGE:815Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
815_wholemount_strong_3D_1.wlz
815_wholemount_moderate_3D_1.wlz
815_wholemount_notDetected_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:815_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: one star
Text Annotation:
StructureLevelPatternNotes
outflow tract
detected detected
regionalPrx1 was expressed in a stream of cells that appeared to transverse the third, fourth and developing sixth branchial arches, entering the aortic sac and outflow tract in a similar fasion to Pax3.
branchial arch
detected detected
regionalPrx1 was expressed in a stream of cells that appeared to transverse the third, fourth and developing sixth branchial arches, entering the aortic sac and outflow tract in a similar fasion to Pax3.
3rd branchial arch
detected detected
regionalPrx1 was expressed in a stream of cells that appeared to transverse the third, fourth and developing sixth branchial arches, entering the aortic sac and outflow tract in a similar fasion to Pax3.
2nd branchial arch
detected detected
1st branchial arch
detected detected
1st branchial arch maxillary component
detected detected
4th branchial arch
detected detected
regionalPrx1 was expressed in a stream of cells that appeared to transverse the third, fourth and developing sixth branchial arches, entering the aortic sac and outflow tract in a similar fasion to Pax3.
limb
detected detected
Prx1 was present in the limb bud.
central nervous system
not detected not detected
Neural tube was negative.
trunk somite
not detected not detected
Somite derivatives were negative.
tail somite
not detected not detected
Somite derivatives were negative.
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:MGI:1334328
Entity Detected:Prrx1, paired related homeobox 1 ( MGI:97712)
Notes:The Prrx1 (Prx1, Pmx) probe used in this study by Conway et al., 1997 [PMID:9053326] was described as "a 450 base pair SmaI fragment (Kern et al., 1994 [PMID:7910581] )". SmaI cuts the sequence submitted by Kern et al to Genbank (U03873.1) once therefore probe end points are unclear.
Chemistry:RNA
Strand:antisense
Specimen
Organism:mouse
Age:10.5 dpc
Theiler Stage:TS17
Mutations:none (wild-type)
Preparation:wholemount
Procedures
General Information
Authors:Conway et al., 1997 [PMID:9053326] Indexed by GXD, Spatially Mapped by EMAGE
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ PMID:9053326] Conway SJ, Henderson DJ, Copp AJ 1997 Pax3 is required for cardiac neural crest migration in the mouse: evidence from the splotch (Sp2H) mutant. Development (124):505-14
 [ doi:10.1006/geno.1994.1066] [ PMID:7910581] Kern MJ, Argao EA, Birkenmeier EH, Rowe LB, Potter SS 1994 Genomic organization and chromosome localization of the murine homeobox gene Pmx. Genomics (19):334-40
Links:MGI:1335055 same experiment
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceMGI