EMAGE mouse gene expression spatial database

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EMAGE:82

Ptch1 patched homolog 1 ( MGI:105373)
TS15 (9.5 dpc)
in situ hybridisation

Data Images


Figure 6B, Theil et al., 1999 [PMID:10409502] . Copyright: This image is from Development and is displayed with the permission of the Company of Biologists Ltd. who owns the copyright

Expression pattern clarity:
Find spatially similar wholemount expression patterns:

Expression Pattern Description

Spatial Annotation:

Annotation colour key:

	strong
	moderate
	weak
	possible
	not detected

wholemount mapping

Download individual expression domains:

82_wholemount_strong_3D_1.wlz

82_wholemount_moderate_3D_1.wlz

82_wholemount_notDetected_3D_1.wlz

(what is wlz format?)

Download all expression domains:

EMAGE:82_all_domains.zip

Find spatially similar wholemount expression patterns:

EMAGE spatially similar wholemount patterns

Morphological match to the template:

Text Annotation:

Structure

Level

Pattern

Notes

neural tube

detected

regional

Expression was restricted to a ventral domain in the neural tube

Annotation Validation:

EMAGE Editor

Detection Reagent

Type:	in situ hybridisation probe
Identifier:	MGI:1277656
Entity Detected:	Ptch1, patched homolog 1 ( MGI:105373)
Sequence:	sense strand is shown >MGI:1277656 ATGGCCTCGGCTGGTAACGCCGCCGGGGCCCTGGGCAGGCAGGCCGGCGGCGGGAGGCGCAGACGGACCG GGGGACCGCACCGCGCCGCGCCGGACCGGGACTATCTGCACCGGCCCAGCTACTGCGACGCCGCCTTCGC TCTGGAGCAGATTTCCAAGGGGAAGGCTACTGGCCGGAAAGCGCCGCTGTGGCTGAGAGCGAAGTTTCAG AGACTCTTATTTAAACTGGGTTGTTACATTCAAAAGAACTGCGGCAAGTTTTTGGTTGTGGGTCTCCTCA TATTTGGGGCCTTCGCTGTGGGATTAAAGGCAGCTAATCTCGAGACCAACGTGGAGGAGCTGTGGGTGGA AGTTGGTGGACGAGTGAGTCGAGAATTAAATTATACCCGTCAGAAGATAGGAGAAGAGGCTATGTTTAAT CCTCAACTCATGATACAGACTCCAAAAGAAGAAGGCGCTAATGTTCTGACCACAGAGGCTCTCCTGCAAC ACCTGGACTCAGCACTCCAGGCCAGTCGTGTGCACGTCTACATGTATAACAGGCAATGGAAGTTGGAACA TTTGTGCTACAAATCAGGGGAACTTATCACGGAGACAGGTTACATGGATCAGATAATAGAATACCTTTAC CCTTGCTTAATCATTACACCTTTGGACTGCTTCTGGGAAGGGGCAAAGCTACAGTCCGGGACAGCATACC TCCTAGGTAAGCCTCCTTTACGGTGGACAAACTTTGACCCCTTGGAATTCCTAGAAGAGTTAAAGAAAAT AAACTACCAAGTGGACAGCTGGGAGGAAATGCTGAATAAAGCCGAAGTTGGCCATGGGTACATGGACCGG CCTTGCCTCAACCCAGCCGACCCAGATTGCCCTGCCACAGCCCCTAACAAAAATTCAACCAAACCTCTTG ATGTGGCCCTTGTTTTGAATGGTGGATGTCAAGGTTTATCCAGGAAGTATATGCATTGGCAGGAGGAGTT GATTGTGGGTGGTACCGTCAAGAATGCCACTGGAAAACTTGTCAGCGCTCACGCCCTGCAAACCATGTTC CAGTTAATGACTCCCAAGCAAATGTATGAACACTTCAGGGGCTACGACTATGTCTCTCACATCAACTGGA ATGAAGACAGGGCAGCCGCCATCCTGGAGGCCTGGCAGAGGACTTACGTGGAGGTGGTTCATCAAAGTGT CGCCCCAAACTCCACTCAAAAGGTGCTTCCCTTCACAACCACGACCCTGGACGACATCCTAAAATCCTTC TCTGATGTCAGTGTCATCCGAGTGGCCAGCGGCTACCTACTGATGCTTGCCTATGCCTGTTTAACCATGC TGCGCTGGGACTGCTCCAAGTCCCAGGGTGCCGTGGGGCTGGCTGGCGTCCTGTTGGTTGCGCTGTCAGT GGCTGCAGGATTGGGCCTCTGCTCCTTGATTGGCATTTCTTTTAATGCTGCGACAACTCAGGTTTTGCCG TTTCTTGCTCTTGGTGTTGGTGTGGATGATGTCTTCCTCCTGGCCCATGCATTCAGTGAAACAGGACAGA ATAAGAGGATTCCATTTGAGGACAGGACTGGGGAGTGCCTCAAGCGCACCGGAGCCAGCGTGGCCCTCAC CTCCATCAGCAATGTCACCGCCTTCTTCATGGCCGCATTGATCCCTATCCCTGCCCTGCGAGCGTTCTCC CTCCAGGCTGCTGTGGTGGTGGTATTCAATTTTGCTATGGTTCTGCTCATTTTTCCTGCAATTCTCAGCA TGGATTTATACAGACGTGAGGACAGAAGATTGGATATTTTCTGCTGTTTCACAAGCCCCTGTGTCAGCAG GGTGATTCAAGTTGAGCCACAGGCCTACACAGAGCCTCACAGTAACACCCGGTACAGCCCCCCACCCCCA TACACCAGCCACAGCTTCGCCCACGAAACCCATATCACTATGCAGTCCACCGTTCAGCTCCGCACAGAGT ATGACCCTCACACGCACGTGTACTACACCACCGCCGAGCCACGCTCTGAGATCTCTGTACAGCCTGTTAC CGTCACCCAGGACAACCTCAGCTGTCAGAGTCCCGAGAGCACCAGCTCTACCAGGGACCTGCTCTCCCAG TTCTCAGACTCCAGCCTCCACTGCCTCGAGCCCCCCTGCACCAAGTGGACACTCTCTTCGTTTGCAGAGA AGCACTATGCTCCTTTCCTCCTGAAACCCAAAGCCAAGGTTGTGGTAATCCTTCTTTTCCTGGGCTTGCT GGGGGTCAGCCTTTATGGGACCACCCGAGTGAGAGACGGGCTGGACCTCACGGACATTGTTCCCCGGGAA ACCAGAGAATATGACTTCATAGCTGCCCAGTTCAAGTACTTCTCTTTCTACAACATGTATATAGTCACCC AGAAAGCAGACTACCCGAATATCCAGCACCTACTTTACGACCTTCATAAGAGTTTCAGCAATGTGAAGTA TGTCATGCTGGAGGAGAACAAGCAACTTCCCCAAATGTGGCTGCACTACTTTAGAGACTGGCTTCAAGGA CTTCAGGATGCATTTGACAGTGACTGGGAAACTGGGAGGATCATGCCAAACAATTATAAAAATGGATCAG ATGACGGGGTCCTCGCTTACAAACTCCTGGTGCAGACTGGCAGCCGAGACAAGCCCATCGACATTAGTCA GTTGACTAAACAGCGTCTGGTAGACGCAGATGGCATCATTAATCCGAGCGCTTTCTACATCTACCTGACC GCTTGGGTCAGCAACGACCCTGTAGCTTACGCTGCCTCCCAGGCCAACATCCGGCCTCACCGGCCGGAGT GGGTCCATGACAAAGCCGACTACATGCCAGAGACCAGGCTGAGAATCCCAGCAGCAGAGCCCATCGAGTA CGCTCAGTTCCCTTTCTACCTCAACGGCCTACGAGACACCTCAGACTTTGTGGAAGCCATAGAAAAAGTG AGAGTCATCTGTAACAACTATACGAGCCTGGGACTGTCCAGCTACCCCAATGGCTACCCCTTCCTGTTCT GGGAGCAATACATCAGCCTGCGCCACTGGCTGCTGCTATCCATCAGCGTGGTGCTGGCCTGCACGTTTCT AGTGTGCGCAGTCTTCCTCCTGAACCCCTGGACGGCCGGGATCATTGTCATGGTCCTGGCTCTGATGACC GTTGAGCTCTTTGGCATGATGGGCCTCATTGGGATCAAGCTGAGTGCTGTGCCTGTGGTCATCCTGATTG CATCTGTTGGCATCGGAGTGGAGTTCACCGTCCACGTGGCTTTGGCCTTTCTGACAGCCATTGGGGACAA GAACCACAGGGCTATGCTCGCTCTGGAACACATGTTTGCTCCCGTTCTGGACGGTGCTGTGTCCACTCTG CTGGGTGTACTGATGCTTGCAGGGTCCGAATTTGATTTCATTGTCAGATACTTCTTTGCCGTCCTGGCCA TTCTCACCGTCTTGGGGGTTCTCAATGGACTGGTTCTGCTGCCTGTCCTCTTATCCTTCTTTGGACCGTG TCCTGAGGTGTCTCCAGCCAATGGCCTAAACCGACTGCCCACTCCTTCGCCTGAGCCGCCTCCAAGTGTC GTCCGGTTTGCCGTGCCTCCTGGTCACACGAACAATGGGTCTGATTCCTCCGACTCGGAGTACAGCTCTC AGACCACGGTGTCTGGCATCAGTGAGGAGCTCAGGCAATACGAAGCACAGCAGGGTGCCGGAGGCCCTGC CCACCAAGTGATTGTGGAAGCCACAGAAAACCCTGTCTTTGCCCGGTCCACTGTGGTCCATCCGGACTCC AGACATCAGCCTCCCTTGACCCCTCGGCAACAGCCCCACCTGGACTCTGGCTCCTTGTCCCCTGGACGGC AAGGCCAGCAGCCTCGAAGGGATCCCCCTAGAGAAGGCTTGCGGCCACCCCCCTACAGACCGCGCAGAGA CGCTTTTGAAATTTCTACTGAAGGGCATTCTGGCCCTAGCAATAGGGACCGCTCAGGGCCCCGTGGGGCC CGTTCTCACAACCCTCGGAACCCAACGTCCACCGCCATGGGCAGCTCTGTGCCCAGCTACTGCCAGCCCA TCACCACTGTGACGGCTTCTGCTTCGGTGACTGTTGCTGTGCATCCCCCGCCTGGACCTGGGCGCAACCC CCGAGGGGGGCCCTGTCCAGGCTATGAGAGCTACCCTGAGACTGATCACGGGGTATTTGAGGATCCTCAT GTGCCTTTTCATGTCAGGTGTGAGAGGAGGGACTCAAAGGTGGAGGTCATAGAGCTACAGGACGTGGAAT GTGAGGAGAGGCCGTGGGGGAGCAGCTCCAACTGA
Notes:	Probe used in this study by Theil et al., 1999 [PMID:10409502] is indicated as being described by Goodrich et al., 1996 [PMID:8595881] ie. "corresponding to M2-3 (which contains the first 841bp of the cDNA clone M2)". M2 contains 97nt of sequence upstream of the AUG which has not been deposited in Genbank. The rest of the 841nt probe sequence corresponds to nt 1-744 of NM_008957.1
Chemistry:	RNA
Strand:	antisense

Specimen

Organism:	mouse
Strain:	C57BL/6 x C3H
Age:	9.5 dpc
Theiler Stage:	TS15
Mutations:	none (wild-type)
Preparation:	wholemount

Procedures

General Information

Authors:	Theil et al., 1999 [PMID:10409502] . Indexed by GXD, Spatially mapped by EMAGE
Submitted by:	EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:	non-screen
References:	[ PMID:10409502] Theil T, Alvarez-Bolado G, Walter A, Ruther U 1999 Gli3 is required for Emx gene expression during dorsal telencephalon development. Development (126):3561-71
	[ doi:10.1101/gad.10.3.301] [ PMID:8595881] Goodrich LV, Johnson RL, Milenkovic L, McMahon JA, Scott MP 1996 Conservation of the hedgehog/patched signaling pathway from flies to mice: induction of a mouse patched gene by Hedgehog. Genes Dev (10):301-12
Links:	MGI:1340424 same experiment
	Ensembl same gene
	Allen Brain Atlas same gene
	BioGPS same gene
	International Mouse Knockout Project Status same gene
	GEISHA Chicken ISH Database same gene
	EMBL-EBI Gene Expression Atlas same gene
	BrainStars same gene
	ViBrism same gene
Data Source