Quicksearch Help

(Click the icon to keep this page displayed.)

EMAGE:821

Otx2 orthodenticle homolog 2 (Drosophila) ( MGI:97451)
TS09 (ES Downs & Davies)
in situ hybridisation

Data Images
EMAGE:821
Fig 1E Kinder et al, 2001 [PMID:11566865] . Copyright: This image is from Development and is displayed with the permission of the Company of Biologists Ltd who owns the copyright.

Expression pattern clarity: three stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Notes:
This embryo is defined by the authors as early streak stage (see Downs & Davies [PMID:8269852] for a description of this staging method). Anterior is to the left.
Expression Pattern Description
Spatial Annotation:
EMAGE:821Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
821_wholemount_strong_3D_1.wlz
821_wholemount_notDetected_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:821_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: two stars
Text Annotation:
StructureLevelPatternNotes
embryo
detected detected
regionalExpression recedes from the posterior germ cell layers as the primitive streak expands anteriorly
primitive streak
not detected not detected
Expression recedes from the posterior germ cell layers as the primitive streak expands anteriorly. The posterior limit of expression borders the anterior of the primitive streak.
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:MGI:2154932
Entity Detected:Otx2, orthodenticle homolog 2 (Drosophila) ( MGI:97451)
Notes:The Otx2 probe used in this study by Kinder et al, 2001 [PMID:11566865] is of undefined sequence.
Chemistry:RNA
Strand:antisense
Label:digoxigenin
Specimen
Organism:mouse
Age:ES Downs & Davies
Theiler Stage:TS09
Mutations:none (wild-type)
Preparation:wholemount
Procedures
Fixation:4% paraformaldehyde
General Information
Authors:Kinder et al, 2001 [PMID:11566865] Indexed by GXD, Spatially mapped by EMAGE
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ PMID:11566865] Kinder SJ, Tsang TE, Wakamiya M, Sasaki H, Behringer RR, Nagy A, Tam PP 2001 The organizer of the mouse gastrula is composed of a dynamic population of progenitor cells for the axial mesoderm. Development (128):3623-34
 [ PMID:8269852] Downs KM, Davies T 1993 Staging of gastrulating mouse embryos by morphological landmarks in the dissecting microscope. Development (118):1255-66
Links:MGI:2154979 same experiment
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceEMAGE