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EMAGE:87

Otx2 orthodenticle homolog 2 (Drosophila) ( MGI:97451)
TS09 (6.75 dpc)
in situ hybridisation

Data Images
EMAGE:87
Figure 4.C, Perea-Gomez et al., 1999 [PMID:10498685] . Copyright: This image is from Development and is displayed with the permission of the Company of Biologists Ltd. who owns the copyright

Expression pattern clarity: three stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Expression Pattern Description
Spatial Annotation:
EMAGE:87Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
87_wholemount_strong_3D_1.wlz
87_wholemount_possible_3D_1.wlz
87_wholemount_notDetected_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:87_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: one star
Text Annotation:
StructureLevelPatternNotes
embryo
detected detected
regionalExpression is restricted to the anterior two thirds of the epiblast
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:MGI:23226
Entity Detected:Otx2, orthodenticle homolog 2 (Drosophila) ( MGI:97451)
Notes:The probe used in this study by Perea-Gomez et al., 1999 [PMID:10498685] is indicated as being described by Ang et al., 1994 [PMID:7607086] ie. "pOtd9", which includes the homeodomain coding region. See Figure 1B of the latter reference for a depiction of the region covered by the probe.
Chemistry:RNA
Strand:antisense
Specimen
Organism:mouse
Age:6.75 dpc
Theiler Stage:TS09
Mutations:none (wild-type)
Preparation:wholemount
Procedures
General Information
Authors:Perea-Gomez et al., 1999 [PMID:10498685] Indexed by GXD, Spatially mapped by EMAGE
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ PMID:10498685] Perea-Gomez A, Shawlot W, Sasaki H, Behringer RR, Ang S 1999 HNF3beta and Lim1 interact in the visceral endoderm to regulate primitive streak formation and anterior-posterior polarity in the mouse embryo. Development (1999):4499-511
 [ PMID:7607086] Ang SL, Conlon RA, Jin O, Rossant J 1994 Positive and negative signals from mesoderm regulate the expression of mouse Otx2 in ectoderm explants. Development (120):2979-89
Links:MGI:1346206 same experiment
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceMGI