Quicksearch Help

(Click the icon to keep this page displayed.)

EMAGE:908

Lefty1 left right determination factor 1 ( MGI:107405)
TS09 (6.5 dpc)
in situ hybridisation

Data Images
EMAGE:908
Fig 6C Perea-Gomez et al, 1999 [PMID:10498685] . Copyright: This image is from Development and is displayed with the permission of the Company of Biologists Ltd who owns the copyright.

Expression pattern clarity: three stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Notes:
Anterior is to the left.
Expression Pattern Description
Spatial Annotation:
EMAGE:908Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
908_wholemount_strong_3D_1.wlz
908_wholemount_notDetected_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:908_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: two stars
Text Annotation:
StructureLevelPatternNotes
primitive endoderm
detected detected
regionalExpression is restricted to the anterior visceral endoderm
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:MGI:1206113
Entity Detected:Lefty1, left right determination factor 1 ( MGI:107405)
Notes:The Leftb (Stra3/lefty1) probe used in this study by Perea-Gomez et al, 1999 [PMID:10498685] is indicated as that described by Oulad-Abdelghani et al, 1998 [PMID:9496783] ie "a labeled Stra3 riboprobe". The actual sequence of this probe is not reported.
Chemistry:RNA
Strand:antisense
Specimen
Organism:mouse
Age:6.5 dpc
Theiler Stage:TS09
Mutations:none (wild-type)
Preparation:wholemount
Procedures
General Information
Authors:Perea-Gomez et al, 1999 [PMID:10498685] Indexed by GXD, Spatially mapped by EMAGE
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ PMID:10498685] Perea-Gomez A, Shawlot W, Sasaki H, Behringer RR, Ang S 1999 HNF3beta and Lim1 interact in the visceral endoderm to regulate primitive streak formation and anterior-posterior polarity in the mouse embryo. Development (1999):4499-511
 [ PMID:9496783] Oulad-Abdelghani M, Chazaud C, Bouillet P, Mattei MG, Dolle P, Chambon P 1998 Stra3/lefty, a retinoic acid-inducible novel member of the transforming growth factor-beta superfamily. Int J Dev Biol (42):23-32
Links:MGI:1346304 same experiment
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceMGI