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EMAGE:935

Dlx2 distal-less homeobox 2 ( MGI:94902)
TS20 (12.5 dpc)
in situ hybridisation

Data Images
EMAGE:935
Figure 5A of Corbin et al., 2003 [PMID:12930780] . Copyright: This image is from Development and is displayed with permission of The Company of Biologists Ltd. who owns the copyright.

Expression pattern clarity: two stars
Find spatially similar expression patterns: Find spatially similar patterns
Notes:
Image annotations: Ctx, cerebral cortex; LGE, lateral ganglionic eminence; MGE, medial ganglionic eminence. Arrow shows the dorsal limit of Dlx2 gene expression.
Expression Pattern Description
Spatial Annotation:
EMAGE:935EMAGE:935Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
3D mapping3D context movie

View mapped 3D expression image EMAGE genex expression entry
Download individual expression domains:
935_voxel_strong_3D_1.wlz
935_voxel_moderate_3D_1.wlz
935_voxel_notDetected_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:935_all_domains.zip
Find spatially similar expression patterns: EMAGE spatially similar patterns
Morphological match to the template: three stars
Text Annotation:
StructureLevelPatternNotes
telencephalon
detected detected
regional
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:MGI:2676160
Entity Detected:Dlx2, distal-less homeobox 2 ( MGI:94902)
Sequence:sense strand is shown

>MGI:2676160
TCGAGGCTTCCCGGCTCTCAGAGGCTCCTTTTTTCTCTCCTGCTCCAGGCCTCAGCTCCAGTCCGCTTCG
GTTATTGACCTCCTGGGTCCTACTCCACCCTATCACCTACCCCCGTGACCCCCGGGATCCCGCCGGTTTT
TTCCCCTCCTGGGGGCTCATGGGGGAGAATTCCAGCTCTCCCAACTCTTCCCGCCTCCCACTTTCCCCAG
GAACACTCCCGTAGCTCCTTCATCCATTGCCAGTGGAGGGTTTTTATTTTTATTTTTTTAAAAGTTTAGG
TGCCTTTGCGGATGACCTCATTTTGATGTTAAAAAAAAACTGATTTTTTTAATATGTGGACGCTGCAAAA
AATGTGTTTAAATTATCTTTTTTAAGATGAATTAAGGACTATTAGCTCGAACTTCGATGCAGAGTTTGTA
AATAAGGGTGTCTGTGCAGATTTCCCCACATTTATTTGTATAAAAATTTCTCATCTTTTCAGACTTTTTT
GTAAACCGCCCCCGAGTTGTGAAAGCTGCGACGTAGCAGTGACCTCAGCAGTCCCTATGTTTTCCCCCTT
TGAAAATTTTTCTCAGTTAAATTAAGCTACTGATTTGAATTTGTTTTTATCTTGTCCTAAAGTCTTTGTT
CTTGAAATGCAAGGTATTTGGGGGTTATTTATTATGAAAGCAACATACTCTTAATGTTGATTTTACAATA
TGAAGAGATTATTTAAAATAAATTATTGTTTT
nt 1671 - nt 2402 of M80540.1
Notes:The Dlx2 (Tes-1) probe used in this study by Corbin et al., 2003 [PMID:12930780] is described as that used by Porteus et al 1991 [PMID:1678612] ie "bases 1371-2102 of the Tes-1 cDNA". The sequence of Tes-1 is shown in Fig 1 therein and in GenBank as M80540 - numbering of these two sequences is out of registration by 300nt.
Chemistry:RNA
Strand:antisense
Label:digoxigenin
Specimen
Organism:mouse
Age:12.5 dpc
Theiler Stage:TS20
Mutations:none (wild-type)
Preparation:section
Procedures
Fixation:4% paraformaldehyde
Embedding:cryosection
General Information
Authors:Corbin et al., 2003 [PMID:12930780] . Indexed by GXD, Spatially mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ doi:10.1242/dev.00717] [ PMID:12930780] Corbin JG, Rutlin M, Gaiano N, Fishell G 2003 Combinatorial function of the homeodomain proteins Nkx2.1 and Gsh2 in ventral telencephalic patterning. Development (130):4895-906
 [ doi:10.1016/0896-6273(91)90260-7] [ PMID:1678612] Porteus MH, Bulfone A, Ciaranello RD, Rubenstein JL 1991 Isolation and characterization of a novel cDNA clone encoding a homeodomain that is developmentally regulated in the ventral forebrain. Neuron (7):221-9
Links:MGI:2676242 same experiment
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceMGI