Quicksearch Help

(Click the icon to keep this page displayed.)

EMAGE:940

Otx2 orthodenticle homolog 2 (Drosophila) ( MGI:97451)
TS08 (6.5 dpc)
in situ hybridisation

Data Images
EMAGE:940 EMAGE:940
Fig 3A Acampora et al, 2001 [PMID:11731460] . Copyright: This image is from Development and is displayed with the permission of the Company of Biologists Ltd who owns the copyright. Fig 3A' Acampora et al, 2001 [PMID:11731460] . Copyright: This image is from Development and is displayed with the permission of the Company of Biologists Ltd who owns the copyright.

Expression pattern clarity: two stars
Find spatially similar expression patterns: Find spatially similar patterns
Notes:
The images shown are described by the authors as adjacent sagittal sections. A is an in situ hybridisation for Otx2 mRNA and A' is an antibody staining for Otx2 protein. Image annotations: epi - epiblast, AVE - anterior visceral endoderm. The arrow points to the AVE.
Expression Pattern Description
Spatial Annotation:
EMAGE:940EMAGE:940Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
3D mapping3D context movie

View mapped 3D expression image EMAGE genex expression entry
Download individual expression domains:
940_voxel_strong_3D_1.wlz
940_voxel_notDetected_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:940_all_domains.zip
Find spatially similar expression patterns: EMAGE spatially similar patterns
Morphological match to the template: one star
Text Annotation:
StructureLevelPatternNotes
epiblast
detected detected
primitive endoderm
detected detected
Expression is described by the authors in the visceral endoderm (VE).
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:MGI:2155180
Entity Detected:Otx2, orthodenticle homolog 2 (Drosophila) ( MGI:97451)
Notes:The probe used in this study by Acampora et al, 2001 [PMID:11731460] is defined as such: "The Otx2 probe for in situ hybridisation on sections corresponds to probe a in Fig. 1A". Exact end points are not defined but it covers part of exons 1 and 2.
Chemistry:RNA
Strand:antisense
Label:undefined
Specimen
Organism:mouse
Age:6.5 dpc
Theiler Stage:TS08
Mutations:none (wild-type)
Preparation:section
Procedures
Staining procedure:undefined
General Information
Authors:Acampora et al, 2001 [PMID:11731460] Indexed by GXD, Spatially mapped by EMAGE
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ PMID:11731460] Acampora D, Boyl PP, Signore M, Martinez-Barbera JP, Ilengo C, Puelles E, Annino A, Reichert H, Corte G, Simeone A 2001 OTD/OTX2 functional equivalence depends on 5' and 3' UTR-mediated control of Otx2 mRNA for nucleo-cytoplasmic export and epiblast-restricted translation. Development (128):4801-13
Links:MGI:2155323 same experiment
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceMGI