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EMAGE:943

Nodal nodal ( MGI:97359)
TS12 (8.5 dpc)
in situ hybridisation

Data Images
EMAGE:943
Fig 5i Norris et al, 2002 [PMID:12091315] . Copyright: This image is from Development and is displayed with the permission of the Company of Biologists Ltd who owns the copyright.

Expression pattern clarity: three stars
Find spatially similar expression patterns: Find spatially similar patterns
Notes:
Image annotations: n, node; llpm, left lateral plate mesoderm; s, somite; L, left; R, right.
Expression Pattern Description
Spatial Annotation:
EMAGE:943EMAGE:943Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
3D mapping3D context movie

View mapped 3D expression image EMAGE genex expression entry
Download individual expression domains:
943_voxel_strong_3D_1.wlz
943_voxel_moderate_3D_1.wlz
943_voxel_notDetected_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:943_all_domains.zip
Find spatially similar expression patterns: EMAGE spatially similar patterns
Morphological match to the template: two stars
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:MGI:1335832
Entity Detected:Nodal, nodal ( MGI:97359)
Notes:The nodal probe used in this study by Norris et al, 2002 [PMID:12091315] is described as that used by Conlon et al, 1994 [PMID:7924997] ie "nucleotides 330-660, cloned into pBluescript KS-II, and transcribed from the T3 promoter". End positions are unknown as these nucleotide positions are not referred to a specific clone.
Chemistry:RNA
Strand:antisense
Specimen
Organism:mouse
Strain:ICR
Age:8.5 dpc
Theiler Stage:TS12
Mutations:none (wild-type)
Preparation:wholemount plus section of wholemount
Procedures
General Information
Authors:Norris et al, 2002 [PMID:12091315] Indexed by GXD, Spatially mapped by EMAGE
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ PMID:12091315] Norris DP, Brennan J, Bikoff EK, Robertson EJ 2002 The Foxh1-dependent autoregulatory enhancer controls the level of Nodal signals in the mouse embryo. Development (129):3455-68
 [ PMID:7924997] Conlon FL, Lyons KM, Takaesu N, Barth KS, Kispert A, Herrmann B, Robertson EJ 1994 A primary requirement for nodal in the formation and maintenance of the primitive streak in the mouse. Development (120):1919-28
Links:MGI:2183524 same experiment
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceMGI