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EMAGE:979

Pax6 paired box gene 6 ( MGI:97490)
TS19 (11.5 dpc)
in situ hybridisation

Data Images
EMAGE:979
Figure 3G of Theil et al., 1999 [PMID:10409502] Copyright: This image is from Development and is displayed with the permission of The Company of Biologists Ltd. who owns the copyright.

Expression pattern clarity: two stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Notes:
Image annotations: ctx - cortex.
Expression Pattern Description
Spatial Annotation:
EMAGE:979Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
979_wholemount_strong_3D_1.wlz
979_wholemount_moderate_3D_1.wlz
979_wholemount_weak_3D_1.wlz
979_wholemount_notDetected_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:979_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: three stars
Text Annotation:
StructureLevelPatternNotes
telencephalon
detected detected
Expression is restricted to the dorsal telencephalon.
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:MGI:1277653
Entity Detected:Pax6, paired box gene 6 ( MGI:97490)
Sequence:sense strand is shown

>MGI:1277653
AATTCTGCAGACCCATGCAGATGCAAAAGTCCAGGTGCTGGACAATGAAAACGTATCCAACGGTTGTGTG
AGTAAAATTCTGGGCAGGTATTACGAGACTGGCTCCATCAGACCCAGGGCAATCGGAGGGAGTAAGCCAA
GAGTGGCGACTCCAGAAGTTGTAAGCAAAATAGCCCAGTATAAACGGGAGTGCCCTTCCATCTTTGCTTG
GGAAATCCGAGACAGATTATTATCCGAGGGGGTCTGTACCAACGATAACATACCCAGTGTGTCATCAATA
AACAGAGTTCTTCGCAACCTGG
nt 294 - nt 595 of X63963.1
Notes:The Pax6 probe used in this study by Theil et al., 1999 [PMID:10409502] is indicated as that used by Walther & Gruss, 1991 [PMID:1687460] ie: "an EcoRI-NheI-cDNA-fragment encoding most of the 3' part of the Pax-6 paired box." Editors Note: Restriction analysis of the sequence from Walther & Gruss (X63963.1) indicates it is likely to be the EcoRI-NheI fragment extending between nt294 and nt595 as the paired box domain extends between nt172 and nt597.
Chemistry:RNA
Strand:antisense
Specimen
Organism:mouse
Strain:C3H x C57BL/6
Age:11.5 dpc
Theiler Stage:TS19
Mutations:none (wild-type)
Preparation:wholemount
Procedures
General Information
Authors:Theil et al., 1999 [PMID:10409502] Indexed by GXD, Spatially Mapped by EMAGE
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ PMID:10409502] Theil T, Alvarez-Bolado G, Walter A, Ruther U 1999 Gli3 is required for Emx gene expression during dorsal telencephalon development. Development (126):3561-71
 [ PMID:1687460] Walther C, Gruss P 1991 Pax-6, a murine paired box gene, is expressed in the developing CNS. Development (113):1435-49
Links:MGI:1340411 same experiment
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceMGI