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EMAGE:986

Gad1 glutamic acid decarboxylase 1 ( MGI:95632)
TS20 (12.5 dpc)
in situ hybridisation

Data Images
EMAGE:986
Figure 7A of Corbin et al., 2003 [PMID:12930780] . Copyright: This image is from Development and is displayed with permission of The Company of Biologists Ltd. who owns the copyright.

Expression pattern clarity: three stars
Find spatially similar expression patterns: Find spatially similar patterns
Notes:
Arrow shows dorsal limit of expression of Gad1 (Gad67).
Expression Pattern Description
Spatial Annotation:
EMAGE:986EMAGE:986Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
3D mapping3D context movie

View mapped 3D expression image EMAGE genex expression entry
Download individual expression domains:
986_voxel_strong_3D_1.wlz
986_voxel_moderate_3D_1.wlz
986_voxel_notDetected_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:986_all_domains.zip
Find spatially similar expression patterns: EMAGE spatially similar patterns
Morphological match to the template: two stars
Text Annotation:
StructureLevelPatternNotes
telencephalon
detected detected
regionalExpression marks developing inhibitory neuron populations.
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:MGI:2676166
Entity Detected:Gad1, glutamic acid decarboxylase 1 ( MGI:95632)
Notes:The Gad1 (Gad67) probe used in this study by Corbin et al., 2003 [PMID:12930780] is described as that used by Behar et al, 1994 [PMID:8131264] . Behar et al describe two Gad1 probes (which detect two alternatively spliced transcripts with differing expression patterns in the rat brain) and it is not defined which of these was used in this study.
Chemistry:RNA
Strand:antisense
Label:digoxigenin
Specimen
Organism:mouse
Age:12.5 dpc
Theiler Stage:TS20
Mutations:none (wild-type)
Preparation:section
Procedures
Fixation:4% paraformaldehyde
Embedding:cryosection
General Information
Authors:Corbin et al., 2003 [PMID:12930780] . Indexed by GXD, Spatially mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ doi:10.1242/dev.00717] [ PMID:12930780] Corbin JG, Rutlin M, Gaiano N, Fishell G 2003 Combinatorial function of the homeodomain proteins Nkx2.1 and Gsh2 in ventral telencephalic patterning. Development (130):4895-906
 [ doi:10.1016/0165-3806(94)90215-1] [ PMID:8131264] Behar T, Ma W, Hudson L, Barker JL 1994 Analysis of the anatomical distribution of GAD67 mRNA encoding truncated glutamic acid decarboxylase proteins in the embryonic rat brain. Brain Res Dev Brain Res (77):77-87
Links:MGI:2676248 same experiment
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceMGI