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EMAGE:1008

Acvr2a activin receptor IIA ( MGI:102806)
TS20 (12.5 dpc)
in situ hybridisation

Data Images
EMAGE:1008 EMAGE:1008
Fig 10B, Feijen et al, 1994 [PMID:7821227] . Copyright: This image is from Development and is displayed with the permission of the Company of Biologists Ltd who owns the copyright. Fig 10B, Feijen et al, 1994 [PMID:7821227] . Copyright: This image is from Development and is displayed with the permission of the Company of Biologists Ltd who owns the copyright.

Expression pattern clarity: two stars
Find spatially similar expression patterns: Find spatially similar patterns
Notes:
Corresponding bright and dark field images are shown. Image annotations: cs, corpus striatum; di, diencephalon; mo, medulla oblongata; te, telencephalon; tg, trigeminal ganglion.
Expression Pattern Description
Spatial Annotation:
EMAGE:1008EMAGE:1008Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
3D mapping3D context movie

View mapped 3D expression image EMAGE genex expression entry
Download individual expression domains:
1008_voxel_strong_3D_1.wlz
1008_voxel_notDetected_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:1008_all_domains.zip
Find spatially similar expression patterns: EMAGE spatially similar patterns
Morphological match to the template: two stars
Text Annotation:
StructureLevelPatternNotes
brain
detected detected
regionalSelectively expressed in the mantle layer
corpus striatum
detected detected
regionalSelectively expressed in the mantle layer
diencephalon lateral wall mantle layer
detected detected
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:MGI:23937
Entity Detected:Acvr2a, activin receptor IIA ( MGI:102806)
Sequence:sense strand is shown

>MGI:23937
ATTTCTGGTTTCATTGAAATAGTGAAGCAAGGTTGTTGGCTGGATGATATCAACTGCTATGACAGGACTG
ATTGTATAGAAAAAAAAGACAGCCCTGAAGTGTACTTTTGTTGCTGTGAGGGCAATATGTGTAATGAAAA
GTTCTCTTATTTTCCGGAGATGGAAGTCACACAGCCCACTTCAAATCCTGTTACACCGAAGCCACCCTAT
TACAACATTCTGCTGTATTCCTTGGTAC
nt 815 - nt 1052 of NM_007396.2
Notes:The probe used in this study by Feijen et al, 1994 [PMID:7821227] is described as: "activin type IIA receptor, a 239 nucleotide SspI-KpnI fragment (Mathews and Vale, 1991 [PMID:1646080] )". The probe end co-ordinates (shown above with reference to NM_007396.2) were deduced from this information.
Chemistry:RNA
Strand:antisense
Label:S35
Specimen
Organism:mouse
Age:12.5 dpc
Theiler Stage:TS20
Mutations:none (wild-type)
Preparation:section
Procedures
Fixation:4% paraformaldehyde
Embedding:paraffin
Staining procedure:autoradiography
General Information
Authors:Feijen et al, 1994 [PMID:7821227] Indexed by GXD, Spatially mapped by EMAGE
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ PMID:7821227] Feijen A, Goumans MJ, van den Eijnden-van Raaij AJ 1994 Expression of activin subunits, activin receptors and follistatin in postimplantation mouse embryos suggests specific developmental functions for different activins. Development (120):3621-37
 [ doi:10.1016/0092-8674(91)90549-E] [ PMID:1646080] Mathews LS, Vale WW 1991 Expression cloning of an activin receptor, a predicted transmembrane serine kinase. Cell (65):973-82
Links:MGI:2135922 same experiment
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceMGI