EMAGE mouse gene expression spatial database

Quicksearch Help

(Click the icon to keep this page displayed.)

EMAGE:10111

Lypd1 Ly6/Plaur domain containing 1 ( MGI:1919835)
TS23 (14.5 dpc)
in situ hybridisation

Data Images


"Pseudo-wholemount" of euxassay_000080. This image has been made by aligning and collapsing the constitutent sections. Information about the method.	euxassay_000080_01	euxassay_000080_02	euxassay_000080_03	euxassay_000080_04

euxassay_000080_05	euxassay_000080_06	euxassay_000080_07	euxassay_000080_08	euxassay_000080_09

euxassay_000080_10	euxassay_000080_11	euxassay_000080_12	euxassay_000080_13	euxassay_000080_14

euxassay_000080_15	euxassay_000080_16	euxassay_000080_17	euxassay_000080_18	euxassay_000080_19

euxassay_000080_20	euxassay_000080_21	euxassay_000080_22	euxassay_000080_23	euxassay_000080_24

View assay images:
Expression pattern clarity:
Find spatially similar wholemount expression patterns:

Expression Pattern Description

Spatial Annotation:

Annotation colour key:

	strong
	moderate
	weak
	possible
	not detected

wholemount mapping

Download individual expression domains:

10111_wholemount_strong.wlz

10111_wholemount_moderate.wlz

10111_wholemount_weak.wlz

10111_wholemount_possible.wlz

10111_wholemount_not_detected.wlz

(what is wlz format?)

Download all expression domains:

EMAGE:10111_all_domains.zip

Find spatially similar wholemount expression patterns:

EMAGE spatially similar wholemount patterns

Morphological match to the template:

Text Annotation:

Structure

Level

Pattern

Notes

caudate-putamen

strong

regional

strong expression: see section 02 03 05

limb

moderate

regional

moderate expression: see section 01

forelimb

moderate

regional

moderate expression: see section 01

arm

moderate

regional

moderate expression: see section 01

hand

moderate

regional

moderate expression: see section 01 02

hand mesenchyme

strong

regional

strong expression: see section 23

carpus

strong

regional

strong expression: see section 23 moderate expression: see section 03 24

hindlimb

moderate

regional

moderate expression: see section 01 05 20

foot

strong

regional

strong expression: see section 22 moderate expression: see section 01 04

foot mesenchyme

strong

regional

strong expression: see section 22 moderate expression: see section 02 05

tarsus

strong

regional

strong expression: see section 21 22 23 moderate expression: see section 02 03 04 05 19 20 24 weak expression: see section 18

thymus primordium

weak

regional

weak expression: see section 13 14 15 16 17

thyroid gland

strong

regional

strong expression: see section 17 weak expression: see section 09 13 15 16

brain

strong

regional

strong expression: see section 10

forebrain

strong

regional

strong expression: see section 10

diencephalon

strong

regional

strong expression: see section 18

pituitary gland

weak

single cell

weak expression: see section 14

neurohypophysis

weak

single cell

weak expression: see section 15 16

skin

moderate

regional

moderate expression: see section 20

vibrissa

strong

regional

strong expression: see section 22 moderate expression: see section 09 20 weak expression: see section 06 21

vibrissa dermal component

strong

regional

strong expression: see section 22 moderate expression: see section 09 20 weak expression: see section 06 21

pineal primordium

moderate

regional

moderate expression: see section 13

hypothalamus

strong

regional

strong expression: see section 04 09 15 moderate expression: see section 10 12 13 16 weak expression: see section 08 14 17 not detected expression: see section 03

hypothalamus mantle layer

moderate

regional

moderate expression: see section 12

diencephalon lamina terminalis

moderate

regional

moderate expression: see section 13 14

thalamus

strong

regional

strong expression: see section 04 06 07 08 09 10 15 16 17 18 19 moderate expression: see section 13 14

interthalamic adhesion

strong

regional

strong expression: see section 07

thalamus mantle layer

strong

regional

strong expression: see section 07 08

telencephalon

strong

regional

strong expression: see section 10 moderate expression: see section 15

cerebral cortex

strong

regional

strong expression: see section 08 23 moderate expression: see section 21 22

cerebral cortex mantle layer

strong

regional

strong expression: see section 02 03 04 05 06 08 17 23 moderate expression: see section 22

cerebral cortex marginal layer

strong

regional

strong expression: see section 08 moderate expression: see section 21

corpus striatum

strong

regional

strong expression: see section 01 02 03 04 05 06 18 19 20 21 22 23 24

caudate nucleus

strong

regional

strong expression: see section 04 05 06

head of caudate nucleus

strong

regional

strong expression: see section 01 04

tail of caudate nucleus

strong

regional

strong expression: see section 04 08

lentiform nucleus

strong

regional

strong expression: see section 08 09

olfactory lobe

strong

regional

strong expression: see section 08 09 10 11 12 15 16 17 moderate expression: see section 14

olfactory cortex

strong

regional

strong expression: see section 08 09 10 11 12 15 16 17 18 weak expression: see section 13

olfactory cortex mantle layer

strong

regional

strong expression: see section 12 16 18

olfactory cortex marginal layer

strong

regional

strong expression: see section 12 16 17

hindbrain

strong

regional

strong expression: see section 07 08 11 18 22

medulla oblongata

strong

regional

strong expression: see section 09 10 11 18

medulla oblongata lateral wall

strong

regional

strong expression: see section 06 09 10 11 20

medulla oblongata alar plate

strong

regional

strong expression: see section 09 10 11 12 13

medulla oblongata alar plate mantle layer

strong

regional

strong expression: see section 11 12 13

medulla oblongata alar plate marginal layer

strong

regional

strong expression: see section 13

medulla oblongata basal plate

strong

regional

strong expression: see section 09 10 11 12 13

medulla oblongata basal plate mantle layer

strong

regional

strong expression: see section 10 11 12 13

medulla oblongata basal plate marginal layer

strong

regional

strong expression: see section 13

medulla oblongata sulcus limitans

strong

regional

strong expression: see section 10 11

metencephalon

strong

regional

strong expression: see section 10 11 13 14 17 18 22

metencephalon lateral wall

strong

regional

strong expression: see section 11 13 19 20 22

metencephalon alar plate

strong

regional

strong expression: see section 06 07 08 09 10 19 22

cerebellum

strong

regional

strong expression: see section 05 06 07 08 09 10 11 12 17 18 19 20 21 22 moderate expression: see section 04 16

cerebellum intraventricular portion

strong

regional

strong expression: see section 17

cerebellum intraventricular portion mantle layer

strong

regional

strong expression: see section 10 11 12

rest of cerebellum

strong

regional

strong expression: see section 05 08 09 10 11 12 17 18 21 22 23 moderate expression: see section 04 16

rest of cerebellum mantle layer

strong

regional

strong expression: see section 08 10 11 12

rest of cerebellum marginal layer

strong

regional

strong expression: see section 08

metencephalon rest of alar plate

strong

regional

strong expression: see section 08 18 19 22 23

metencephalon basal plate

strong

regional

strong expression: see section 08 09 10 11 12 13 14 16 18 19 20

pons

strong

regional

strong expression: see section 07 08 09 10 11 12 18 19

pons mantle layer

strong

regional

strong expression: see section 08 09 10 12

metencephalon sulcus limitans

strong

regional

strong expression: see section 09 10 11 12 14 16

midbrain

strong

regional

strong expression: see section 07 08 09 10 11 14 15 16 17 18 19 weak expression: see section 12

midbrain lateral wall

strong

regional

strong expression: see section 06 07 08 09 10 11 12 15 16 17 18 19 20

midbrain mantle layer

strong

regional

strong expression: see section 06 07 08 09 10 11 12 14 15 16 17 18 19 20

midbrain marginal layer

strong

regional

strong expression: see section 07 08 09 10 11 14 16 17 18 19

tegmentum

strong

regional

strong expression: see section 09 11 12 14 15 16 17 19

central nervous system ganglion

strong

regional

strong expression: see section 11

facial vii ganglion

strong

regional

strong expression: see section 03 05 06 08 11 13 19 20 21 22 23 moderate expression: see section 04

glossopharyngeal ix ganglion

strong

regional

strong expression: see section 03 05 06 07 08 09 10 11 12 19 20 22 23 moderate expression: see section 04

trigeminal v ganglion

strong

regional

strong expression: see section 03 05 06 07 08 09 10 19 20 21 22 23 24 moderate expression: see section 04 18

vagus x ganglion

strong

regional

strong expression: see section 03 05 06 07 08 09 10 11 19 20 21 22 23 moderate expression: see section 04 18

inferior vagus x ganglion

strong

regional

strong expression: see section 19 23 moderate expression: see section 13 15

superior vagus x ganglion

strong

regional

strong expression: see section 19 20

vestibulocochlear viii ganglion

strong

regional

strong expression: see section 03 05 06 07 08 09 10 11 19 20 21 22 23 24 moderate expression: see section 04 weak expression: see section 18

vestibulocochlear viii ganglion cochlear component

strong

regional

strong expression: see section 24

vestibulocochlear viii ganglion vestibular component

strong

regional

strong expression: see section 24

facial vii nerve

strong

regional

strong expression: see section 09 13 weak expression: see section 14

glossopharyngeal ix nerve

strong

regional

strong expression: see section 13 weak expression: see section 14

hypoglossal xii nerve

strong

regional

strong expression: see section 10 13

olfactory i nerve

strong

regional

strong expression: see section 05 07 09 10 20 moderate expression: see section 04 08 11 weak expression: see section 06

optic ii nerve

strong

regional

strong expression: see section 05 07 09 20 22 23 moderate expression: see section 08 weak expression: see section 21

trigeminal v nerve

strong

regional

strong expression: see section 07

trigeminal v nerve mandibular division

strong

regional

strong expression: see section 10 20 moderate expression: see section 08 weak expression: see section 21

trigeminal v nerve maxillary division

strong

regional

strong expression: see section 13 20 moderate expression: see section 08 weak expression: see section 21

trigeminal v nerve ophthalmic division

strong

regional

strong expression: see section 23 24

trochlear iv nerve

strong

regional

strong expression: see section 07 moderate expression: see section 08

vestibulocochlear viii nerve

strong

regional

strong expression: see section 07 10 23

spinal cord

strong

regional

strong expression: see section 16 17 19

spinal cord lateral wall

strong

regional

strong expression: see section 15 16 18 19

spinal cord mantle layer

strong

regional

strong expression: see section 14 16

alar columns

strong

regional

strong expression: see section 13 14 15 16 17 18 19

basal columns

strong

regional

strong expression: see section 13 14 15 16 17 18 19

spinal ganglion

moderate

single cell

moderate expression: see section 14

dorsal root ganglion

strong

single cell

strong expression: see section 20 moderate expression: see section 14 15 21 weak expression: see section 12 16

otic capsule

moderate

regional

moderate expression: see section 01 02 10 11

inner ear vestibular component

moderate

regional

moderate expression: see section 02

retina

weak

regional

weak expression: see section 04

pigmented retinal epithelium

strong

single cell

strong expression: see section 02 moderate expression: see section 03 23 weak expression: see section 01 04 24

nasal meatus

weak

regional

weak expression: see section 17

naris

moderate

regional

moderate expression: see section 15

external naris

weak

regional

weak expression: see section 17

posterior naris

weak

regional

weak expression: see section 17

posterior naris epithelium

moderate

regional

moderate expression: see section 13 weak expression: see section 16

primary choana

moderate

regional

moderate expression: see section 13 weak expression: see section 16 17

nasal capsule

moderate

regional

moderate expression: see section 19 weak expression: see section 20

nasal cavity

weak

regional

weak expression: see section 17

nasal septum

moderate

regional

moderate expression: see section 15

viscerocranium

moderate

regional

Expression in the turbinate bone.

lower jaw incisor

strong

regional

strong expression: see section 12 13 16 17 moderate expression: see section 18

upper jaw incisor

strong

regional

strong expression: see section 11 12 13 16 17

Annotation Validation:

spatial mapping by EMAGE editor, text annotation by author

Detection Reagent

Type:	in situ hybridisation probe
Identifier:	T1518
Entity Detected:	Lypd1, Ly6/Plaur domain containing 1 ( MGI:1919835)
Sequence:	sense strand is shown >T1518 TCCTGCTCTTGCCCGCTCCCGGCCCTGCCGATCCGGGAGGATGTGGGTTCTCGGCATCGCAGCAACTTTT TGCGGATTGTTCTGGCTTCCAGGGCTGGCGCTGCAAATTCAGTGCTACCAGTGTGAAGAATTCCAGCTGA ACAACGATTGCTCATCCCCTGAGTTCATCGTAAATTGCACCGTGAACGTTCAAGACATGTGTCAGAAAGA AGTGATGGAGCAAAGTGCTGGGATCATGTACCGGAAGCCGTGTGCATCGTCAGCAGCCTGTCTCATTGCT TCAGCTGGGTACCAGTCCTTCTGTTCCCCTGGGAAACTGAACTCCGTGTGCATCAGCTGCTGCAACACCC CTCTTTGCAATGGGCCGAGGCCCAAGAAGAGAGGCAGCTCTGCCTCGGCCATCAGGCCAGGGCTTCTCAC CACTCTCCTGTTCTTCCACTTAGCCCTCTGCTTGGCACACTGCTGAAGCTAGAGGAGATGCCAACCCCTG CTGCCTCACCTGTCTGGCCCTTCGTCTCT
Notes:	The probe template was PCR amplified from IMAGE:790114 using vector specific primers. Forward Primer - name:RZPD M13 forward, sequence:GCTATTACGCCAGCTGGCGAAAGGGGGATGTG; Reverse Primer - name:RZPD M13 reverse, sequence:CCCCAGGCTTTACACTTTATGCTTCCGGCTCG. Anti-sense probe was then transcribed from the PCR amplified template using Sp6 polymerase. EMAGE Editor's Note: the partial probe sequence indicated here was given by the EURExpress Consortium and has been checked using BLAST comparison against all available partial insert sequences of IMAGE:790114 from NCBI. In cases where no BLAST hit was found (because the two sequence reads are found at opposing ends of the insert sequence), both end sequences were then checked against the appropriate cDNA RefSeq to ensure validity of the information.
Chemistry:	RNA
Strand:	antisense
Label:	digoxigenin

Specimen

Organism:	mouse
Strain:	C57BL/6
Age:	14.5 dpc
Theiler Stage:	TS23
Mutations:	none (wild-type)
Preparation:	section

Procedures

Fixation:	none
Embedding:	cryosection (OCT)
Staining procedure:	alkaline phosphatase + NBT/BCIP

General Information

Authors:	Dr. Graciana Diez-Roux, Prof. Gregor Eichele, Prof. Richard Baldock, Dr. Duncan Davidson, Prof. Stylianos Antonarakis, Dr. Marie Laure Yaspo, Prof. Salvador Martinez Perez, Dr. Pascal Dolle, Dr. David Tannahill, Prof. Pier Paolo Di Fiore, Mr. Stefan Kruse, Mr. Paolo Sarmientos, Dr. Uwe Radelof, Prof. Andrea Ballabio.
Principal investigator:	Professor Andrea Ballabio, Fondazione Telethon, TIGEM Instituto di Genetica e Medicina, Via Pietro Castellino 111 80131, Napoli, Italy 80131
Submitted by:	EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:	screen
References:	[ doi:10.1371/journal.pbio.1000582] [ PMID:21267068] Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, et al 2011 A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo PLoS Biol (9)
Links:	EMAGE:10110 same embryo
	EMAGE:10109 same embryo
	EMAGE:10108 same embryo
	EurExpress:euxassay_000080 same experiment
	MGI:4826037 same experiment
	Ensembl same gene
	Allen Brain Atlas same gene
	BioGPS same gene
	International Mouse Knockout Project Status same gene
	GEISHA Chicken ISH Database same gene
	EMBL-EBI Gene Expression Atlas same gene
	BrainStars same gene
	ViBrism same gene
Data Source