EMAGE mouse gene expression spatial database

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EMAGE:12435

Ctnna2 catenin (cadherin associated protein), alpha 2 ( MGI:88275)
TS23 (14.5 dpc)
in situ hybridisation

Data Images


"Pseudo-wholemount" of euxassay_011120. This image has been made by aligning and collapsing the constitutent sections. Information about the method.	euxassay_011120_01	euxassay_011120_02	euxassay_011120_03	euxassay_011120_04

euxassay_011120_05	euxassay_011120_06	euxassay_011120_07	euxassay_011120_08	euxassay_011120_09

euxassay_011120_10	euxassay_011120_11	euxassay_011120_12	euxassay_011120_13	euxassay_011120_14

euxassay_011120_15	euxassay_011120_16	euxassay_011120_17	euxassay_011120_18	euxassay_011120_19

euxassay_011120_20	euxassay_011120_21	euxassay_011120_22	euxassay_011120_23

View assay images:
Expression pattern clarity:
Find spatially similar wholemount expression patterns:

Expression Pattern Description

Spatial Annotation:

Annotation colour key:

	strong
	moderate
	weak
	possible
	not detected

wholemount mapping

Download individual expression domains:

12435_wholemount_strong.wlz

12435_wholemount_moderate.wlz

12435_wholemount_weak.wlz

12435_wholemount_possible.wlz

12435_wholemount_not_detected.wlz

(what is wlz format?)

Download all expression domains:

EMAGE:12435_all_domains.zip

Find spatially similar wholemount expression patterns:

EMAGE spatially similar wholemount patterns

Morphological match to the template:

Text Annotation:

Structure

Level

Pattern

Notes

anterior abdominal wall musculature

moderate

regional

moderate expression: see section 01 02 03 04 05 06 07 08 09 10 15 16 17 18 19 20 21 22 23

adrenal medulla

weak

regional

weak expression: see section 09 10 11 18 19

thymus primordium

moderate

spotted

moderate expression: see section 13 14 15 weak expression: see section 16 17

thyroid gland

weak

spotted

weak expression: see section 17

brain

strong

regional

strong expression: see section 01 02 03 04 05 06 07 08 09 10 11 12 13 15 16 17 18 19 20 21 22 23

dermis

moderate

regional

moderate expression: see section 01 02 03 04 05 06 07 08 09 10 11 12 13 14 15 16 17 18 19 20 21 22 23

vibrissa dermal component

moderate

regional

moderate expression: see section 04 05 23

facial vii ganglion

strong

regional

strong expression: see section 05 06 07 08 19 20 21 22

glossopharyngeal ix ganglion

strong

regional

strong expression: see section 07 08 18 19

trigeminal v ganglion

strong

regional

strong expression: see section 03 04 05 06 07 08 09 10 18 19 20 21 22

vagus x ganglion

strong

regional

strong expression: see section 09 18

vestibulocochlear viii ganglion

strong

regional

strong expression: see section 06 07 08 09 18 19 20 21

trigeminal v nerve

strong

regional

strong expression: see section 10 11

spinal cord

strong

regional

strong expression: see section 11 12 13 15 16 17 18

cervico-thoracic ganglion

strong

regional

strong expression: see section 11 12 13 17

cervical ganglion

strong

regional

strong expression: see section 10 18

thoracic ganglion

strong

regional

strong expression: see section 14 15 16

dorsal root ganglion

strong

regional

strong expression: see section 08 09 10 11 12 13 16 17 18 19

inner ear

strong

regional

strong expression: see section 02 03 04 05 20 21 22 23

neural retina

strong

regional

strong expression: see section 01 02 03 04 23

anterior naris

strong

regional

strong expression: see section 13 16 17 moderate expression: see section 12

nasal cavity olfactory epithelium

strong

regional

strong expression: see section 08 09 10 11 12 13 14 15 16 17 18 19

vomeronasal organ

strong

regional

strong expression: see section 12 13 15 16

heart valve

moderate

regional

moderate expression: see section 13 14 15 16 weak expression: see section 12

esophagus

moderate

regional

moderate expression: see section 13 14 15

tongue

strong

spotted

strong expression: see section 13 15 16 17

stomach

strong

regional

strong expression: see section 01 02 03 04 05 06 07 08 09 10 11

rectum

strong

regional

strong expression: see section 13 14

midgut

strong

regional

strong expression: see section 08 09 10 11 12 13 14 15 16 17 18 19 20

lower lip

strong

regional

strong expression: see section 09 10 11 12 13 14 15 16 17 18 19

lower jaw molar

strong

regional

strong expression: see section 08 19

upper lip

strong

regional

strong expression: see section 09 10 11 12 13 14 15 16 17 18 19

upper jaw molar

strong

regional

strong expression: see section 08 19

seminiferous cord

moderate

regional

moderate expression: see section 06 07 08 09 20 21 22 23

left lung

moderate

regional

moderate expression: see section 04 05 06 07 08 09 10 11 12 13 14

right lung

moderate

regional

moderate expression: see section 15 16 17 18 19 20 21 22 23

facial bone primordium

strong

regional

strong expression: see section 05 06 07 09 10 18 19 20 21 22

Annotation Validation:

spatial mapping by EMAGE editor, text annotation by author

Detection Reagent

Type:	in situ hybridisation probe
Identifier:	T9342
Entity Detected:	Ctnna2, catenin (cadherin associated protein), alpha 2 ( MGI:88275)
Sequence:	sense strand is shown >T9342 GGAGACCCGGGCGGAGCGGGCGGCACCGCACCTCGGCCAGAAGCAGCTGCAGCAGCTGCCCTAGTCCCCA CCGCCGCCTCTCCAGCAGCTTCTGTCATTCCGCGCCAGCTGCTGCAGACAGAGGACGAGGAGGAGGAGGC GAGAAACTCCCACCGACCCACAGAGAGGCCGTGAGACCAGTTGTTAGCATTCAAGTCAGGAGGCTCATAG CTCCAGTGCCAGGAGGTTTTACTATGACAGATATTCACTCAAGCTACACATACACAGGGAGCATGACTTC GGCAACTTCACCTATTATTTTAAAATGGGATCCCAAAAGTTTGGAAATCCGGACACTCACAGTGGAAAGA CTATTGGAGCCACTTGTGACACAGGTGACAACACTTGTCAACACAAGCAACAAAGGTCCGTCTGGTAAAA AGAAAGGGAGGTCAAAGAAAGCCCATGTGCTGGCAGCATCTGTAGAACAAGCTACTCAGAACTTCCTGGA AAAGGGTGAACAGATCGCTAAGGAGAGCCAAGACCTCAAAGAAGAGTTAGTGGCTGCTGTAGAGGATGTG CGGAAGCAAGGTGAGACAATGCGGATTGCCTCCTCAGAGTTTGCAGATGACCCTTGCTCTTCTGTCAAGC GTGGCACCATGGTGCGTGCAGCACGGGCTCTGCTATCGGCTGTGACACGCTTGCTCATCCTGGCCGACAT GGCAGATGTCATGAGGCTTTTATCGCATCTGAAAATTGTCGAGGAGGCCTTGGAAGCAGTCAAAAATGCC ACAAATGAACAAGACCTTGCAAACCGATTTAAAGAGTTTGGGAAAGAGATGGTGAAACTGAACTATGTAG CAGCAAGACGGCAGCAGGAGCTCAAGGACCCTCACTGTAGGGATGAGATGGCTGCAGCCCGTGGAGCCCT GAAGAAGAATGCCACCATGCTGTACACAGCCTCCCAAGCCTTCCTCCGGCATCCAGATGTTGCTGCTACA AGAGCCAACCGAGATTATGTATTTAAACAAGTCCAAGAGGCCATAGCTGGCATCTCCAGTGCTGCTCAGG CCACCTCCCCCACCGATGAAGCCAAAGGCCACACAGGCATCGGCGAGCTGGCTGCAGCCCTGAATGAGTT TGATAATAAGATCATCCTGGACCCCATGACATTCAGCGAGGCCAGGTTCCGACCATCCCTGGAGGAGAGA CTGGAGAGCATCATCAGTGGGGCTGCTCTCATGGCAGATTCCTCCTGCACACGTGATGACCGCCGTGAGC GTATTGTGGCCGAGTGCAATGCAGTTCGACAGGCACTCCAGGACCTGCTAAGCGAGTACATGAATAACAC TGGAAGGAAAGAGAAAGGAGACCCTCTCAACATTGCGATTGACAAGATGACCAAGAAAACAAGAGATCTG AGGAGACAGCTTCGGAAAGCTGTGATGGATCACATCTCAGATTCTTTCTTGGAAACCAATGTCCCCTTGC TGGTTCTCATTGAGGCTGCGAAGAGCGGGAATGAGAAGGAGGTGAAGGAATACGCCCAAGTTTTCCGTGA ACATGCCAACAAGCTGGTGGAGGTTGCCAATTTGGCTTGTTCCATCTCCAACAATGAGGAAGGGGTGAAA TTAGTCAGAATGGCAGCCACCCAGATTGACAGCCTGTGTCCCCAAGTCATTAATGCTGCCCTCACACTGG CTGCTCGGCCACAGAGTAAAGTTGCTCAGGACAACATGGATGTCTTCAAAGACCAGTGGGAAAAGCAAGT CCGTGTGCTCACTGAGGCAGTGGATGACATCACCTCTGTGGATGACTTCCTCTCTGTCTCAGAAAACCAT ATCTTGGAGGATGTGAACAAATGTGTGATTGCCCTGCAAGAGGGAGATGTGGACACACTGGATCGCACAG CTGGGGCCATACGGGGCCGGGCAGCCCGGGTCATTCACATCATCAATGCAGAGATCGAGAACTATGAAGC TGGGGTCTATACAGAGAAAGTGCTGGAAGCCACAAAATTGCTTTCAGAAACAGTGATGCCACGCTTTGCT GAACAAGTTGAGGTGGCCATCGAAGCCCTGAGCGCCAATGTCCCTCAGCCATTCGAGGAGAACGAGTTCA TCGATGCCTCGCGCCTGGTGTATGACGGTGTTCGGGACATCAGAAAGGCTGTGCTGATGATCAGGACTCC AGAAGAGCTAGAAGATGATTCCGACTTTGAGCAAGAGGATTATGTGCGGAGTCGGACAAGTGTTCAGACA GAGGACGACCAGCTCATTGCTGGACAGAGTGCACGGGCCATCATGGCGCAACTACCACAGGAGGAGAAAG CAAAAATAGCTGAACAGGTGGAGATTTTCCACCAAGAAAAAAGCAAGCTGGATGCTGAAGTGGCCAAGTG GGATGACAGCGGCAATGACATCATTGTGCTGGCCAAGCAGATGTGTATGATCATGATGGAGATGACAGAC TTCACAAGAGGCAAAGGCCCACTGAAAAATACATCTGATGTCATTAATGCTGCCAAGAAGATTGCAGAAG CAGGCTCTCGAATGGACAAATTAGCGCGCGCTGTGGCTGATCAGTGTCCTGATTCAGCATGTAAGCAGGA TTTATTAGCCTACCTTCAGCGGATTGCTTTGTACTGCCATCAGCTTAACATCTGCAGCAAAGTGAAGGCC GAGGTTCAGAACCTAGGAGGAGAGCTCATTGTGTCAGGGACAGGAGTTCAGAGCACTTTCACTACCTTTT ATGAGGTAGATTGTGATGTCATAGATGGGGGCAGGGCTAGTCAACTTTCTACCCACCTCCCAACCTGTGC TGAGGGAGCTCCAATCGGGAGTGGAAGCAGTGACTCCTCCATGCTGGACAGTGCTACATCACTCATCCAG GCAGCCAAAAACCTGATGAATGCTGTTGTCCTCACGGTGAAAGCGTCTTATGTAGCCTCAACTAAATACC AGAAGGTCTATGGAACAGCAGCTGTCAACTCTCCAGTTGTGTCTTGGAAGATGAAGGCTCCTGAAAAGAA GCCCCTTGTGAAGAGAGAAAAGCCTGAAGAATTCCAGACAAGAGTTAGACGGGGGTCTCAAAAGAAACAC ATTTCACCTGTGCAGGCTTTAAGTGAATTCAAGGCAATGGATTCCTTCTAGGACAATAGGCTACAAACAA GAAAGCTTTTTCTTTCCCTCCTCCCCCTTTCTTTTTCATTTTGATTCCATTTTTTGTAAGCATACCTGCT GACTTGTCTGCCTCTGGCATGGGGAAATTAAGAGAACAGTGTCTGTTTGCATGTTAGACGAGATGAGATC AATGCTGCTGGTCTATCAGTAGCCTCGGAAGGGGACAGGTGACAATTTCTGTCCTGAGGTGGAACAGAGC TGTCCTTTGCAACATTCTCTTAAAGTTGGGCAAAGAGTTCACACTGTGATGTTCACGGGAGTGGGAGGGA TGGGGAAAATAAACTTAACTCTACAAAAGCAAACTCTAATGCATGCAAGAACCATTAGGTTGGCAGGTAT ATTCATAAGTGAAAAACCTGGAAGTGTAATGGTAGAACATAAAACCTGTACTGCTTCTGTTTGAGTGCAA AACTGTACTAGCCAATACGCTGAAGTGTGTGGCCCACAAATTGAAATTTTAACCTCAATGTCCTGTATCC ATGCTCTCATGTGGATTCTTAACTGAGGAGAAACTAACTCATCCCGTCTCAAATGTTTCTTTAATCTGCA TTCTGTTCTTTCTTCCTGGTAGTGCCATTACTAGTGTTCCTCTTATTTTCTCCCCTCTGCTGAAGACAAT AAATATTCCTTTGAGACCCGTGGATCCTTCTGCGGACCCTAATGACACAAAGTGGAGCTCAACTGTCCTC CCTTCTATTTCTTTCTTTCTAAACTTGAACTCTGACTTTGCTAGACATAGAAGGCTCAGTGGTGGAACGT TAGCGAAATGGAGATTGACAGTATGTGAAGGCTTAGAGGCAAATGCATAGGTGTGTAGCTGAGAGTGCTG GTATCTAATATACCATTGTATTCACTGACACAAAATAAACACATTTAATCTTGAAAAAAAAAAAAAAAAA AA
Notes:	The probe template was PCR amplified from IMAGE:6850068 using vector (pYX-Asc) specific primers. Forward Primer - name:RZPD T3, sequence:ATTAACCCTCACTAAAGGGA; Reverse Primer - name:RZPD T7, sequence:TAATACGACTCACTATAGGG. Anti-sense probe was then transcribed from the PCR amplified template using T7 polymerase. EMAGE Editor's Note: the probe sequence indicated here was given by the EURExpress Consortium and has been checked using a computational method whereby a BLAST comparison was made against the full insert sequence of IMAGE:6850068 which was retrieved directly from NCBI.
Chemistry:	RNA
Strand:	antisense
Label:	digoxigenin

Specimen

Organism:	mouse
Strain:	C57BL/6
Age:	14.5 dpc
Theiler Stage:	TS23
Mutations:	none (wild-type)
Preparation:	section

Procedures

Fixation:	none
Embedding:	cryosection (OCT)
Staining procedure:	alkaline phosphatase + NBT/BCIP

General Information

Authors:	Dr. Graciana Diez-Roux, Prof. Gregor Eichele, Prof. Richard Baldock, Dr. Duncan Davidson, Prof. Stylianos Antonarakis, Dr. Marie Laure Yaspo, Prof. Salvador Martinez Perez, Dr. Pascal Dolle, Dr. David Tannahill, Prof. Pier Paolo Di Fiore, Mr. Stefan Kruse, Mr. Paolo Sarmientos, Dr. Uwe Radelof, Prof. Andrea Ballabio.
Principal investigator:	Professor Andrea Ballabio, Fondazione Telethon, TIGEM Instituto di Genetica e Medicina, Via Pietro Castellino 111 80131, Napoli, Italy 80131
Submitted by:	EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:	screen
References:	[ doi:10.1371/journal.pbio.1000582] [ PMID:21267068] Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, et al 2011 A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo PLoS Biol (9)
Links:	EMAGE:12437 same embryo
	EMAGE:12434 same embryo
	EMAGE:12436 same embryo
	EMAGE:12433 same embryo
	EMAGE:12438 same embryo
	EurExpress:euxassay_011120 same experiment
	MGI:4824107 same experiment
	Ensembl same gene
	Allen Brain Atlas same gene
	BioGPS same gene
	International Mouse Knockout Project Status same gene
	GEISHA Chicken ISH Database same gene
	EMBL-EBI Gene Expression Atlas same gene
	BrainStars same gene
	ViBrism same gene
Data Source