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EMAGE:191

Foxa2 forkhead box A2 ( MGI:1347476)
TS13 (8.5 dpc)
in situ hybridisation

Data Images
EMAGE:191
Fig 5C, Chang et al, 1999 [PMID:10079226] . Copyright: This image is from Development and is displayed with permission of The Company of Biologists Ltd. who owns the copyright.

Expression pattern clarity: three stars
Find spatially similar expression patterns: Find spatially similar patterns
Notes:
Abbreviations used: fp, floorplate of neural tube; fg, foregut; hg, hindgut; nc, notochord; nt, neural tube.
Expression Pattern Description
Spatial Annotation:
EMAGE:191EMAGE:191Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
3D mapping3D context movie

View mapped 3D expression image EMAGE genex expression entry
Download individual expression domains:
191_voxel_strong_3D_1.wlz
191_voxel_notDetected_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:191_all_domains.zip
Find spatially similar expression patterns: EMAGE spatially similar patterns
Morphological match to the template: one star
Text Annotation:
StructureLevelPatternNotes
foregut diverticulum
strong strong
hindgut diverticulum
strong strong
notochord
strong strong
neural tube
strong strong
regionalExpression is detected in several areas of the developing brain and neural tube.
future brain
strong strong
regionalExpression is detected in several areas of the developing brain and neural tube.
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:MGI:18239
Entity Detected:Foxa2, forkhead box A2 ( MGI:1347476)
Notes:The Foxa2 (HNF-3beta) probe used in this study by Chang et al, 1999 [PMID:10079226] is indicated as being originally described by Ang et al, 1993 [PMID:8306889] ie. as a "HNF-3beta probe", "synthesized from a 566bp cDNA consisting mostly of unique sequences outside the DNA binding domain"
Chemistry:RNA
Strand:antisense
Label:S35
Specimen
Organism:mouse
Age:8.5 dpc
Theiler Stage:TS13
Mutations:none (wild-type)
Preparation:section
Procedures
Staining procedure:autoradiography
General Information
Authors:Chang et al, 1999 [PMID:10079226] Indexed by GXD, Spatially mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ PMID:10079226] Chang H, Huylebroeck D, Verschueren K, Guo Q, Matzuk MM, Zwijsen A 1999 Smad5 knockout mice die at mid-gestation due to multiple embryonic and extraembryonic defects. Development (126):1631-42
 [ PMID:8306889] Ang SL, Wierda A, Wong D, Stevens KA, Cascio S, Rossant J, Zaret KS 1993 The formation and maintenance of the definitive endoderm lineage in the mouse: involvement of HNF3/forkhead proteins. Development (119):1301-15
Links:MGI:1334630 same experiment
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceMGI