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EMAGE:3244

Myog myogenin ( MGI:97276)
TS18 (10.75 dpc)
in situ hybridisation

Data Images
EMAGE:3244
Fig5C of Brohmann et al, 2000 [PMID:10603359] . This image is from Brohmann et al., Development 127: 437-45 (2000), and is displayed with the permission of The Company of Biologists Limited who owns the Copyright.

Expression pattern clarity: three stars
Find spatially similar expression patterns: Find spatially similar patterns
Notes:
Image annotations: Arrowhead = the hypoglossal stream contains myogenin-positive cells. Arrow = myogenin-positive cells at the endpoint of the migration.
Expression Pattern Description
Spatial Annotation:
EMAGE:3244EMAGE:3244Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
3D mapping3D context movie

View mapped 3D expression image EMAGE genex expression entry
Download individual expression domains:
3244_voxel_strong_3D_1.wlz
3244_voxel_notDetected_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:3244_all_domains.zip
Find spatially similar expression patterns: EMAGE spatially similar patterns
Morphological match to the template: two stars
Text Annotation:
StructureLevelPatternNotes
1st branchial arch
detected detected
regionalExpression in the hypoglossal stream. The cells are at the endpoint of migration.
head mesenchyme
detected detected
regionalExpression in the hypoglossal stream. The cells are at the endpoint of migration.
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:MGI:1309773
Entity Detected:Myog, myogenin ( MGI:97276)
Notes:The myogenin probe used in this study by Brohmann et al, 2000 [PMID:10603359] is indicated as that originally described in Sassoon et al., 1989 [PMID:2552320] i.e. "corresponding to the terminal 700 nucleotides of the cDNA, which is specific for myogenin transcripts".
Chemistry:RNA
Strand:antisense
Label:digoxigenin
Specimen
Organism:mouse
Strain:involves: 129P2/OlaHsd
Age:10.75 dpc
Theiler Stage:TS18
Mutations:Lbx1tm1Cbm/Lbx1+
Preparation:sectioned wholemount
Procedures
Fixation:4% paraformaldehyde
General Information
Authors:Brohmann H; Jagla K; Birchmeier C, 2000 [PMID:10603359] . Indexed by GXD, Spatially mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ PMID:10603359] Brohmann H, Jagla K, Birchmeier C 2000 The role of Lbx1 in migration of muscle precursor cells. Development (127):437-45
 [ doi:10.1038/341303a0] [ PMID:2552320] Sassoon D, Lyons G, Wright WE, Lin V, Lassar A, Weintraub H, Buckingham M 1989 Expression of two myogenic regulatory factors myogenin and MyoD1 during mouse embryogenesis. Nature (341):303-7
Links:MGI:2136982 same experiment
 MGI:2136963 allele description
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceMGI