Quicksearch Help

(Click the icon to keep this page displayed.)

EMAGE:3266

Adrbk1 adrenergic receptor kinase, beta 1 ( MGI:87940)
TS17 (10.5 dpc)
in situ hybridisation

Data Images
EMAGE:3266
Fig 2C Sefton et al, 2000 [PMID:11044616] Copyright: Reprinted with permission from Elsevier from [doi:10.1016/S0925-4773(00)00441-X] Mech Dev 98: 127-31, Sefton M; Blanco MJ; Penela P; Mayor F; Nieto MA, Expression of the G protein-coupled receptor kinase 2 during early mouse embryogenesis Copyright 2000

Expression pattern clarity: two stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Notes:
Image annotation: ba - branchial arches.
Expression Pattern Description
Spatial Annotation:
EMAGE:3266Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
3266_wholemount_strong_3D_1.wlz
3266_wholemount_moderate_3D_1.wlz
3266_wholemount_weak_3D_1.wlz
3266_wholemount_possible_3D_1.wlz
3266_wholemount_notDetected_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:3266_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: three stars
Text Annotation:
StructureLevelPatternNotes
1st branchial arch mandibular component mesenchyme derived from neural crest
detected detected
1st branchial arch maxillary component mesenchyme derived from neural crest
detected detected
2nd branchial arch mesenchyme derived from neural crest
detected detected
3rd branchial arch mesenchyme derived from neural crest
detected detected
4th branchial arch mesenchyme derived from neural crest
detected detected
limb
detected detected
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:MGI:2386869
Entity Detected:Adrbk1, adrenergic receptor kinase, beta 1 ( MGI:87940)
Notes:Two Adrbk1 (GRK2) probes were used in this study by Sefton et al, 2000 [PMID:11044616] . They are described as "a NotI/SacI (540 bp) and a HindIII/SpHI (933bp) fragments subcloned from the complete mouse cDNA, which correspond to the amino and carboxy-terminal domains of the GRK2 protein, respectively". Editor's Note: it is unclear from the manuscript whether the two probes were mixed together to produce this result or if one or the other was used alone.
Chemistry:RNA
Strand:antisense
Specimen
Organism:mouse
Strain:BALB/c
Age:10.5 dpc
Theiler Stage:TS17
Mutations:none (wild-type)
Preparation:wholemount
Procedures
Fixation:4% paraformaldehyde
General Information
Authors:Sefton M, Blanco MJ, Penela P, Mayor F, Nieto MA (2000) [PMID:11044616] . Indexed by GXD, Spatially mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ doi:10.1016/S0925-4773(00)00441-X] [ PMID:11044616] Sefton M, Blanco MJ, Penela P, Mayor F, Nieto MA 2000 Expression of the G protein-coupled receptor kinase 2 during early mouse embryogenesis. Mech Dev (98):127-31
Links:MGI:2386962 same experiment
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceMGI