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EMAGE:3362

Bmp4 bone morphogenetic protein 4 ( MGI:88180)
TS20 (12.0 dpc)
in situ hybridisation

Data Images
EMAGE:3362 EMAGE:3362
Fig 2G, Jung et al 1999 [PMID:10330496] .Copyright: Reprinted with permission from Elsevier from [doi:10.1016/S0925-4773(98)00234-2] Mech Dev 81: 179-82, Jung HS; Oropeza V; Thesleff I, Shh, Bmp-2, Bmp-4 and Fgf-8 are associated with initiation and patterning of mouse tongue papillae. Copyright 1999 Fig 1K, Jung et al 1999 [PMID:10330496] .Copyright: Reprinted with permission from Elsevier from [doi:10.1016/S0925-4773(98)00234-2] Mech Dev 81: 179-82, Jung HS; Oropeza V; Thesleff I, Shh, Bmp-2, Bmp-4 and Fgf-8 are associated with initiation and patterning of mouse tongue papillae. Copyright 1999

Expression pattern clarity: three stars
Find spatially similar expression patterns: Find spatially similar patterns
Notes:
The wholemount-stained tongue depicted in 1K was sectioned on a vibratome in the plane indicated to produce section 2G.
Expression Pattern Description
Spatial Annotation:
EMAGE:3362EMAGE:3362Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
3D mappingspatial mapping

View mapped 3D expression image EMAGE genex expression entry
Download individual expression domains:
3362_voxel_strong_3D_1.wlz
3362_voxel_possible_3D_1.wlz
3362_voxel_notDetected_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:3362_all_domains.zip
Find spatially similar expression patterns: EMAGE spatially similar patterns
Morphological match to the template: two stars
Text Annotation:
StructureLevelPatternNotes
lateral lingual swelling epithelium
detected detected
spottedExpression in spots in the posterior part of the tongue and weakly in rows of spots running parallel to the median sulcus in the anterior part
median lingual swelling epithelium
detected detected
spottedExpression in spots in the posterior part of the tongue and weakly in rows of spots running parallel to the median sulcus in the anterior part
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:MGI:2671097
Entity Detected:Bmp4, bone morphogenetic protein 4 ( MGI:88180)
Notes:The Bmp4 probe used in this study by Jung et al, 1999 [PMID:10330496] , is of unspecified sequence.
Chemistry:RNA
Strand:antisense
Label:digoxigenin
Specimen
Organism:mouse
Strain:involves: CBA * NMRI
Age:12.0 dpc
Theiler Stage:TS20
Mutations:none (wild-type)
Preparation:sectioned wholemount
Procedures
Fixation:4% paraformaldehyde
Embedding:gelatin/albumin
General Information
Authors:Jung HS, Oropeza V, Thesleff I, 1999 [PMID:10330496] . Indexed by GXD, Spatially mapped by EMAGE
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ doi:10.1016/S0925-4773(98)00234-2] [ PMID:10330496] Jung HS, Oropeza V, Thesleff I 1999 Shh, Bmp-2, Bmp-4 and Fgf-8 are associated with initiation and patterning of mouse tongue papillae. Mech Dev (81):179-82
Links:MGI:2671103 same experiment
 EMAGE:3358 same embryo
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceMGI