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EMAGE:3409

Hand2 heart and neural crest derivatives expressed transcript 2 ( MGI:103580)
TS16 (10 dpc)
in situ hybridisation

Data Images
EMAGE:3409
Figure 1C of Thomas et al., 1998 [PMID:9671575] . Copyright: This image is from Thomas, et al., Development 125:3005-3014 (1998), and is displayed with the permission of The Company of Biologists Limited who owns the Copyright.

Expression pattern clarity: two stars
Find spatially similar expression patterns: Find spatially similar patterns
Notes:
Note: ba, branchial arches; e, epithelium; m, mesenchyme; nt, neural tube.
Expression Pattern Description
Spatial Annotation:
EMAGE:3409EMAGE:3409Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
3D mappingspatial mapping

View mapped 3D expression image EMAGE genex expression entry
Download individual expression domains:
3409_voxel_strong_3D_1.wlz
3409_voxel_moderate_3D_1.wlz
3409_voxel_notDetected_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:3409_all_domains.zip
Find spatially similar expression patterns: EMAGE spatially similar patterns
Morphological match to the template: two stars
Text Annotation:
StructureLevelPatternNotes
1st branchial arch maxillary component ectoderm
not detected not detected
homogeneousThere was no expression in the epithelial layer of the branchial arch
1st branchial arch maxillary component mesenchyme derived from neural crest
detected detected
regionalThere was no expression in the epithelial layer of the branchial arch or in migratory neural crest cells. Transcripts were concentrated in the neural-crest-derived mesenchyme just underlying the most exterior portion of the branchial arches.
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:MGI:1331691
Entity Detected:Hand2, heart and neural crest derivatives expressed transcript 2 ( MGI:103580)
Notes:The Hand2 (dHAND) probe used in this study by Thomas et al., 1998 [PMID:9671575] is of undefined sequence.
Chemistry:RNA
Strand:antisense
Label:digoxigenin
Specimen
Organism:mouse
Age:10 dpc
Theiler Stage:TS16
Mutations:none (wild-type)
Preparation:section
Procedures
Fixation:4% paraformaldehyde
Embedding:paraffin
General Information
Authors:Thomas T; Kurihara H; Yamagishi H; Kurihara Y; Yazaki Y; Olson EN ; Srivastava D, 1998 [PMID:9671575] . Indexed by GXD, Spatially mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ PMID:9671575] Thomas T, Kurihara H, Yamagishi H, Kurihara Y, Yazaki Y, Olson EN, Srivastava D 1998 A signaling cascade involving endothelin-1, dHAND and msx1 regulates development of neural-crest-derived branchial arch mesenchyme. Development (125):3005-14
Links:MGI:1331697 same experiment
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceMGI