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EMAGE:3429

Nkx3-2 NK3 homeobox 2 ( MGI:108015)
TS15 (9.5 dpc)
in situ hybridisation

Data Images
EMAGE:3429
Figure 3D of Hecksher-Sorensen J; Watson RP; Lettice LA; Serup P; Eley L; De Angelis C; Ahlgren U; Hill RE, 2004 [PMID:15329346] . Copyright: This image is from Hecksher-Sorensen J, Development 2004 Oct;131(19):4665-75 and is displayed with the permission of The Company of Biologists Limited who owns the Copyright.

Expression pattern clarity: two stars
Find spatially similar expression patterns: Find spatially similar patterns
Notes:
Note: arrowheads denote higher expression on the leftward side.
Expression Pattern Description
Spatial Annotation:
EMAGE:3429EMAGE:3429Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
3D mappingspatial mapping

View mapped 3D expression image EMAGE genex expression entry
Download individual expression domains:
3429_voxel_strong_3D_1.wlz
3429_voxel_moderate_3D_1.wlz
3429_voxel_notDetected_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:3429_all_domains.zip
Find spatially similar expression patterns: EMAGE spatially similar patterns
Morphological match to the template: two stars
Text Annotation:
StructureLevelPatternNotes
mesenchyme
detected detected
regionalExpression is bilateral in the splanchnic mesodermal plate (SMP), but is higher on the leftward side.
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:MGI:3510433
Entity Detected:Nkx3-2, NK3 homeobox 2 ( MGI:108015)
Notes:The Bapx1 probe used in this study by Hecksher-Sorensen et al., 2004 [PMID:15329346] is indicated as that originally used by Lettice et al., 1999 [PMID:11523821] , which is of undefined sequence.
Chemistry:RNA
Strand:antisense
Label:digoxigenin
Specimen
Organism:mouse
Age:9.5 dpc
Theiler Stage:TS15
Mutations:none (wild-type)
Preparation:section
Procedures
Staining procedure:alkaline phosphatase + Fast Red
General Information
Authors:Hecksher-Sorensen J; Watson RP; Lettice LA; Serup P; Eley L; De Angelis C; Ahlgren U; Hill RE, 2004 [PMID:15329346] . Indexed by GXD, Spatially mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ doi:10.1242/dev.01364] [ PMID:15329346] Hecksher-Sorensen J, Watson RP, Lettice LA, Serup P, Eley L, De Angelis C, Ahlgren U, Hill RE 2004 The splanchnic mesodermal plate directs spleen and pancreatic laterality, and is regulated by Bapx1/Nkx3.2. Development (131):4665-75
 [ PMID:11523821] Lettice L, Hecksher-S�rensen J, Hill R 2001 The role of Bapx1 (Nkx3.2) in the development and evolution of the axial skeleton. J Anat (199):181-7
Links:MGI:3510660 same experiment
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceMGI