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EMAGE:3438

Hand2 heart and neural crest derivatives expressed transcript 2 ( MGI:103580)
TS18 (10.5 dpc)
in situ hybridisation

Data Images
EMAGE:3438 EMAGE:3438
Figure 3I of Ruest et al., 2004 [PMID:15306564] . Copyright: This image is from Ruest LB, Development 2004 Sep;131(18):4413-23 and is displayed with the permission of The Company of Biologists Limited who owns the Copyright. Figure 3K of Ruest et al., 2004 [PMID:15306564] . Copyright: This image is from Ruest LB, Development 2004 Sep;131(18):4413-23 and is displayed with the permission of The Company of Biologists Limited who owns the Copyright.

Expression pattern clarity: two stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Notes:
Note: 1 and 2, pharyngeal arches 1 and 2.
Expression Pattern Description
Spatial Annotation:
EMAGE:3438Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
3438_wholemount_strong_3D_1.wlz
3438_wholemount_moderate_3D_1.wlz
3438_wholemount_possible_3D_1.wlz
3438_wholemount_notDetected_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:3438_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: two stars
Text Annotation:
StructureLevelPatternNotes
1st branchial arch mandibular component
detected detected
2nd branchial arch
detected detected
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:MGI:1330181
Entity Detected:Hand2, heart and neural crest derivatives expressed transcript 2 ( MGI:103580)
Notes:The Hand2 probe used in this study by Ruest et al., 2004 [PMID:15306564] was originally described in Srivastava et al., 1997 [PMID:9171826] as a "partial dHAND [Hand2] (nucleotide 292-644) cDNA". Editors note: The exact probe sequence is unspecified as this nucleotide numbering is not related to any particular Hand2 sequence.
Chemistry:RNA
Strand:antisense
Label:digoxigenin
Specimen
Organism:mouse
Age:10.5 dpc
Theiler Stage:TS18
Mutations:none (wild-type)
Preparation:wholemount
Procedures
General Information
Authors:Ruest LB; Xiang X; Lim KC; Levi G; Clouthier DE, 2004 [PMID:15306564] . Indexed by GXD, Spatially mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ doi:10.1242/dev.01291] [ PMID:15306564] Ruest LB, Xiang X, Lim KC, Levi G, Clouthier DE 2004 Endothelin-A receptor-dependent and -independent signaling pathways in establishing mandibular identity. Development (131):4413-23
 [ doi:10.1038/ng0697-154] [ PMID:9171826] Srivastava D, Thomas T, Lin Q, Kirby ML, Brown D, Olson EN 1997 Regulation of cardiac mesodermal and neural crest development by the bHLH transcription factor, dHAND. Nat Genet (16):154-60
Links:MGI:3510694 same experiment
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceMGI