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EMAGE:3474

Gbx2 gastrulation brain homeobox 2 ( MGI:95668)
TS11 (7.7 dpc)
in situ hybridisation

Data Images
EMAGE:3474
Fig2E.Copyright: Reprinted with permission from Elsevier from [doi:10.1016/S1567-133X(03)00056-5] Gene Expr Patterns 3: 497-501, Acampora D; Annino A; Puelles E; Alfano I; Tuorto F; Simeone A, OTX1 compensates for OTX2 requirement in regionalisation of anterior neuroectoderm. Copyright 2003

Expression pattern clarity: two stars
Find spatially similar expression patterns: Find spatially similar patterns
Expression Pattern Description
Spatial Annotation:
EMAGE:3474EMAGE:3474Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
3D mappingspatial mapping

View mapped 3D expression image EMAGE genex expression entry
Download individual expression domains:
3474_voxel_strong_3D_1.wlz
3474_voxel_notDetected_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:3474_all_domains.zip
Find spatially similar expression patterns: EMAGE spatially similar patterns
Morphological match to the template: two stars
Text Annotation:
StructureLevelPatternNotes
embryo
detected detected
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:MGI:1321259
Entity Detected:Gbx2, gastrulation brain homeobox 2 ( MGI:95668)
Sequence:sense strand is shown

>MGI:1321259
CCGTCGCTGATGATGATGCAGCGCCCGCTGGGGAGTAGTACCGCCTTCAGCATAGACTCGCTGATCGGCA
GCCCGCCGCAGCCCAGTCCCGGCCATTTCGTCTACACCGGCTACCCCATGTTCATGCCCTACCGGCCGGT
GGTGCTGCCGCCACCGCCGCCACCGCCTCCCGCGCTGCCCCAGGCAGCGCTGCAGCCCGCTCTGCCGCCC
GCGCACCCTCACCACCAGATCCCCAGCCTGCCCACCGGCTTCTGCTCCAGCCTGGCGCAGGGCATGGCGC
TCACCTCCACGCTCATGGCCACTCTGCCCGGCGGCTTCTCTGCGTCGCCCCAGCACCAAGAGGCGGCGGC
TGCCCGCAAGTTCGCTCCACAGCCACTGCCCGGAGGCGGCAACTTCGACAAAGCCGAGGCGCTCCAAGCG
GATGCGGAAGACGGCAAAGCCTTCTTGGCCAAGGAGGGCTCGCTGCTCGCTTTCTCTGCGGCCGAAGCGG
TGCAGGCGTCGCTCGTCGGGGCTGTCCGAGGGCAAGGGAAAGACGAGTCAAAGGTGGAAGATGACCCGAA
GGGCAAGGAGGAGAGCTTCTCTCTGGAGAGCGATGTGGATTACAGCTCAGATGACAATTTGCCTGGTCAG
ACTGCTCATAAGGAAGAAGACCCCGGCCACGCACTGGAGGAGACCCCGCAGAGCGGCGGTGCAGCAGGCA
GCACCACGTCCACAGGCAAGAACCGGCGGCGGCGGACTGCCTTCACCAGCGAACAGCTGCTGGAGCTGGA
GAAAGAATTCCACTGCAAAAAGTACCTCTCCCTGACCGAGCGCTCACAGATCGCCCACGCCCTCAAACTC
AGCGAGGTGCAAGTAAAAATCTGG
nt 441 - nt 1304 of NM_010262.1
Notes:The Gbx2 probe used in this study by Acampora et al., 2003 [PMID:12915318] is indicated as that originally described in Acampora et al., 1998 [PMID:9811592] as a "PCR fragment including the region between aa 6 and aa 294". Editor's note: the co-ordinates shown above were deduced from this information.
Chemistry:RNA
Strand:antisense
Specimen
Organism:mouse
Age:7.7 dpc
Theiler Stage:TS11
Mutations:none (wild-type)
Preparation:section
Procedures
General Information
Authors:Acampora D; Annino A; Puelles E; Alfano I; Tuorto F; Simeone A, 2003 [PMID:12915318] , Indexed by GXD, Spatially Mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ doi:10.1016/S1567-133X(03)00056-5] [ PMID:12915318] Acampora D, Annino A, Puelles E, Alfano I, Tuorto F, Simeone A 2003 OTX1 compensates for OTX2 requirement in regionalisation of anterior neuroectoderm. Gene Expr Patterns (3):497-501
 [ PMID:9811592] Acampora D, Avantaggiato V, Tuorto F, Briata P, Corte G, Simeone A 1998 Visceral endoderm-restricted translation of Otx1 mediates recovery of Otx2 requirements for specification of anterior neural plate and normal gastrulation. Development (125):5091-104
 [ doi:10.1006/geno.1997.4969] [ PMID:9417909] Chapman G, Remiszewski JL, Webb GC, Schulz TC, Bottema CD, Rathjen PD 1997 The mouse homeobox gene, Gbx2: genomic organization and expression in pluripotent cells in vitro and in vivo. Genomics (46):223-33
Links:MGI:3045231 same experiment
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceMGI