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EMAGE:3575

Fgf8 fibroblast growth factor 8 ( MGI:99604)
TS15 (9.5-9.75 dpc)
in situ hybridisation

Data Images
EMAGE:3575
Fig2M.Copyright: Reprinted with permission from Elsevier from [doi:10.1016/S0925-4773(02)00018-7] Mech Dev 113: 163-8, Lin W; Furthauer M; Thisse B; Thisse C; Jing N; Ang SL, Cloning of the mouse Sef gene and comparative analysis of its expression with Fgf8 and Spry2 during embryogenesis. Copyright 2002

Expression pattern clarity: three stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Notes:
Image annotations: MHB - mid-hindbrain boundary, fb - forebrain, lb - limb bud, tb - tailbud, * - branchial arches.
Expression Pattern Description
Spatial Annotation:
EMAGE:3575Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
3575_wholemount_strong_3D_1.wlz
3575_wholemount_moderate_3D_1.wlz
3575_wholemount_notDetected_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:3575_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: three stars
Text Annotation:
StructureLevelPatternNotes
limb
detected detected
tail
detected detected
future midbrain
detected detected
regionalExpression is in the mid/hindbrain boundary region and extends posterior to the isthmus
future hindbrain
detected detected
regionalExpression is in the mid/hindbrain boundary region and extends posterior to the isthmus
telencephalon
detected detected
Expression is in the commissural plate
1st branchial pouch
detected detected
regionalExpression is in the extreme lateral region
2nd branchial pouch
detected detected
regionalExpression is in the extreme lateral region
3rd branchial pouch
detected detected
regionalExpression is in the extreme lateral region
2nd branchial groove ectoderm
detected detected
1st branchial groove ectoderm
detected detected
3rd branchial groove ectoderm
detected detected
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:MGI:1336711
Entity Detected:Fgf8, fibroblast growth factor 8 ( MGI:99604)
Notes:The Fgf8 probe used in this study by Lin et al, 2002 [PMID:11960706] is described as a "Fgf8 cDNA (Crossley et al., 1995 [PMID:7768185] )". Editors note: Crossley et al describe several different length chick cDNA clones. It is not stipulated which was used here.
Chemistry:RNA
Strand:antisense
Specimen
Organism:mouse
Strain:CD-1
Age:9.5-9.75 dpc
Theiler Stage:TS15
Mutations:none (wild-type)
Preparation:wholemount
Procedures
General Information
Authors:Lin W; Furthauer M; Thisse B; Thisse C; Jing N; Ang SL. 2002 [PMID:11960706]
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ doi:10.1016/S0925-4773(02)00018-7] [ PMID:11960706] Lin W, F�rthauer M, Thisse B, Thisse C, Jing N, Ang SL 2002 Cloning of the mouse Sef gene and comparative analysis of its expression with Fgf8 and Spry2 during embryogenesis. Mech Dev (113):163-8
 [ PMID:7768185] Crossley PH, Martin GR 1995 The mouse Fgf8 gene encodes a family of polypeptides and is expressed in regions that direct outgrowth and patterning in the developing embryo. Development (121):439-51
Links:MGI:3040281 same experiment
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceMGI