EMAGE mouse gene expression spatial database

Quicksearch Help

(Click the icon to keep this page displayed.)

EMAGE:3621

Neurod1 neurogenic differentiation 1 ( MGI:1339708)
TS16 (10 dpc)
in situ hybridisation

Data Images


Figure S1K. Copyright: This image is from Raft S, Development 2004;131():1801-1812 and is displayed with the permission of The Company of Biologists Limited who owns the Copyright.	Figure S1L. Copyright: This image is from Raft S, Development 2004;131():1801-1812 and is displayed with the permission of The Company of Biologists Limited who owns the Copyright.	Figure S1M. Copyright: This image is from Raft S, Development 2004;131():1801-1812 and is displayed with the permission of The Company of Biologists Limited who owns the Copyright.	Figure S1O. Copyright: This image is from Raft S, Development 2004;131():1801-1812 and is displayed with the permission of The Company of Biologists Limited who owns the Copyright.	Figure S1O. Copyright: This image is from Raft S, Development 2004;131():1801-1812 and is displayed with the permission of The Company of Biologists Limited who owns the Copyright.

Expression pattern clarity:
Find spatially similar expression patterns:

Notes:

Note: Red arrows mark the medial extent of the signal. Cyan asterisks indicate increased expression and red asterisks indicate ectopic expression.

Expression Pattern Description

Spatial Annotation:

Annotation colour key:

	strong
	moderate
	weak
	possible
	not detected

3D mapping

spatial mapping

View mapped 3D expression image

Download individual expression domains:

3621_voxel_moderate_3D_1.wlz

3621_voxel_notDetected_3D_1.wlz

3621_voxel_strong_3D_1.wlz

3621_voxel_moderate_3D_2.wlz

3621_voxel_notDetected_3D_2.wlz

3621_voxel_strong_3D_2.wlz

3621_voxel_moderate_3D_3.wlz

3621_voxel_notDetected_3D_3.wlz

3621_voxel_strong_3D_3.wlz

3621_voxel_moderate_3D_4.wlz

3621_voxel_notDetected_3D_4.wlz

3621_voxel_strong_3D_4.wlz

3621_voxel_moderate_3D_5.wlz

3621_voxel_notDetected_3D_5.wlz

3621_voxel_strong_3D_5.wlz

(what is wlz format?)

Download all expression domains:

EMAGE:3621_all_domains.zip

Find spatially similar expression patterns:

Morphological match to the template:

Text Annotation:

Structure

Level

Pattern

Notes

otocyst

detected

regional

There is an incresed accumulation of delaminated, expressing cells.

Annotation Validation:

EMAGE Editor

Detection Reagent

Type:	in situ hybridisation probe
Identifier:	MGI:1202579
Entity Detected:	Neurod1, neurogenic differentiation 1 ( MGI:1339708)
Notes:	The Neurod1 probe used in this study by Raft et al., 2004 [PMID:15084464] was originally described in Lee et al., 1995 [PMID:7754368] as "a murine...neuroD [Neurod1] RNA probe (1.7 kb)".
Chemistry:	RNA
Strand:	antisense
Label:	digoxigenin

Specimen

Organism:	mouse
Strain:	involves: 129/Sv * C57BL/6J * FVB * SJL
Age:	10 dpc
Theiler Stage:	TS16
Mutations:	Tbx1^tm1Rak/Tbx1⁺
Preparation:	section

Procedures

Fixation:	4% paraformaldehyde
Embedding:	paraffin

General Information

Authors:	Raft S; Nowotschin S; Liao J; Morrow BE, 2004 [PMID:15084464] . Indexed by GXD, Spatially mapped by EMAGE.
Submitted by:	EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:	non-screen
References:	[ doi:10.1242/dev.01067] [ PMID:15084464] Raft S, Nowotschin S, Liao J, Morrow BE 2004 Suppression of neural fate and control of inner ear morphogenesis by Tbx1. Development (131):1801-12
	[ doi:10.1126/science.7754368] [ PMID:7754368] Lee JE, Hollenberg SM, Snider L, Turner DL, Lipnick N, Weintraub H 1995 Conversion of Xenopus ectoderm into neurons by NeuroD, a basic helix-loop-helix protein. Science (268):836-44
Links:	MGI:3044708 same experiment
	MGI:2179191 allele description
	Ensembl same gene
	Allen Brain Atlas same gene
	BioGPS same gene
	International Mouse Knockout Project Status same gene
	GEISHA Chicken ISH Database same gene
	EMBL-EBI Gene Expression Atlas same gene
	BrainStars same gene
	ViBrism same gene
Data Source