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EMAGE:3653

Foxd4 forkhead box D4 ( MGI:1347467)
TS11 (7.75 dpc)
in situ hybridisation

Data Images
EMAGE:3653
Figure 2B. Copyright: This image is from Rhinn et al., Development 125:845-856 (1998), and is displayed with the permission of The Company of Biologists Limited who owns the Copyright.

Expression pattern clarity: three stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Notes:
Note: Anterior is to the left. Scale bar, 100 um.
Expression Pattern Description
Spatial Annotation:
EMAGE:3653Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
3653_wholemount_strong_3D_1.wlz
3653_wholemount_notDetected_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:3653_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: two stars
Text Annotation:
StructureLevelPatternNotes
embryo mesoderm
detected detected
regionalFkh2 [Foxd4] is expressed in the axial mesoderm.
future brain
detected detected
Fkh2 [Foxd4] is expressed in the presumptive forebrain and midbrain.
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:MGI:1315060
Entity Detected:Foxd4, forkhead box D4 ( MGI:1347467)
Notes:The Foxd4 (fkh-2) probe used in this study by Rhinn et al., 1998 [PMID:9449667] is indicated as that originally described by Kaestner et al., 1995 [PMID:8530406] i.e. a probe "outside the conserved winged helix domain to exclude the possibility of cross-hybridization with the mRNAs of related genes (probe B in Fig. 1)". Editors note: Not enough information is included in Fig1 to deduce the exact sequence of this probe.
Chemistry:RNA
Strand:antisense
Specimen
Organism:mouse
Strain:(CD-1 x 129/Sv)F1
Age:7.75 dpc
Theiler Stage:TS11
Mutations:none (wild-type)
Preparation:wholemount
Procedures
Fixation:4% paraformaldehyde
General Information
Authors:Rhinn M; Dierich A; Shawlot W; Behringer RR; Le Meur M; Ang SL, 1998 [PMID:9449667] . Indexed by GXD, Spatially mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ PMID:9449667] Rhinn M, Dierich A, Shawlot W, Behringer RR, Le Meur M, Ang SL 1998 Sequential roles for Otx2 in visceral endoderm and neuroectoderm for forebrain and midbrain induction and specification. Development (125):845-56
 [ doi:10.1074/jbc.270.50.30029] [ PMID:8530406] Kaestner KH, Monaghan AP, Kern H, Ang SL, Weitz S, Lichter P, Schutz G 1995 The mouse fkh-2 gene. Implications for notochord, foregut, and midbrain regionalization. J Biol Chem (270):30029-35
Links:MGI:1315074 same experiment
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceMGI