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EMAGE:3662

Foxa1 forkhead box A1 ( MGI:1347472)
TS14 (9.5 dpc)
in situ hybridisation

Data Images
EMAGE:3662 EMAGE:3662
Fig4B.Copyright: This image is from Kanai-Azuma et al., Development 129:2367-2379 (2002), and is displayed with the permission of The Company of Biologists Limited who owns the Copyright. Fig4D.Copyright: This image is from Kanai-Azuma et al., Development 129:2367-2379 (2002), and is displayed with the permission of The Company of Biologists Limited who owns the Copyright.

Expression pattern clarity: three stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Find spatially similar expression patterns: Find spatially similar patterns
Notes:
The section plane of D is shown in B.
Expression Pattern Description
Spatial Annotation:
EMAGE:3662EMAGE:3662EMAGE:3662Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
3D mappingspatial mappingwholemount mapping

View mapped 3D expression image EMAGE genex expression entry
Download individual expression domains:
3662_wholemount_strong_3D_2.wlz
3662_wholemount_moderate_3D_1.wlz
3662_wholemount_weak_3D_1.wlz
3662_wholemount_notDetected_3D_2.wlz
3662_voxel_strong_3D_1.wlz
3662_voxel_notDetected_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:3662_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Find spatially similar expression patterns: EMAGE spatially similar patterns
Morphological match to the template: three stars
Text Annotation:
StructureLevelPatternNotes
gut
detected detected
Expression is present in the gut endoderm
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:MGI:19191
Entity Detected:Foxa1, forkhead box A1 ( MGI:1347472)
Notes:The Foxa1 (HNF-3a) probe used in this study by Kanai-Azuma et al, 2002 [PMID:11973269] is indicated as that used by Sasaki & Hogan, 1993 [PMID:8375339] i.e. it was transcribed from the entire 2.0kb insert of a clone called c24. Editors note: the region of the Foxa1 cDNA that clone c24 covers is not defined by the Sasaki & Hogan.
Chemistry:RNA
Strand:antisense
Label:digoxigenin
Specimen
Organism:mouse
Strain:involves: 129S1/Sv
Age:9.5 dpc
Theiler Stage:TS14
Mutations:Sox17tm1Ysk/Sox17+
Preparation:sectioned wholemount
Procedures
Staining procedure:alkaline phosphatase + NBT/BCIP
General Information
Authors:Kanai-Azuma M; Kanai Y; Gad JM; Tajima Y; Taya C; Kurohmaru M; Sanai Y; Yonekawa H; Yazaki K; Tam PP; Hayashi Y (2002) [PMID:11973269] . Indexed by GXD, Spatially mapped by EMAGE
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ PMID:11973269] Kanai-Azuma M, Kanai Y, Gad JM, Tajima Y, Taya C, Kurohmaru M, Sanai Y, Yonekawa H, Yazaki K, Tam PP, Hayashi Y 2002 Depletion of definitive gut endoderm in Sox17-null mutant mice. Development (129):2367-79
 [ PMID:8375339] Sasaki H, Hogan BL 1993 Differential expression of multiple fork head related genes during gastrulation and axial pattern formation in the mouse embryo. Development (118):47-59
Links:MGI:2180032 same experiment
 MGI:2179440 allele description
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceMGI