Quicksearch Help

(Click the icon to keep this page displayed.)

EMAGE:3813

Uncx UNC homeobox ( MGI:108013)
TS14 (9.5 dpc)
in situ hybridisation

Data Images
EMAGE:3813 EMAGE:3813
Fig6C of Dunwoodie et al, 2002 [PMID:11923214] . Copyright: This image is from Dunwoodle et al. Development 129:1795-1806 (2002), and is displayed with the permission of The Company of Biologists Limited who owns the Copyright. Fig6F of Dunwoodie et al, 2002 [PMID:11923214] . Copyright: This image is from Dunwoodle et al. Development 129:1795-1806 (2002), and is displayed with the permission of The Company of Biologists Limited who owns the Copyright.

Expression pattern clarity: two stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Notes:
The tissue in Fig6F has been dissected from the embryo in Fig6C below and shows that expression is restricted to the posterior of the epithelial somites.
Expression Pattern Description
Spatial Annotation:
EMAGE:3813Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
3813_wholemount_strong_3D_1.wlz
3813_wholemount_possible_3D_1.wlz
3813_wholemount_notDetected_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:3813_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: two stars
Text Annotation:
StructureLevelPatternNotes
trunk somite
strong strong
regionalExpression marks the posterior nascent somite and later, the posterior lateral sclerotome. Authors report that expression shows clear periodicity.
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:MGI:1100363
Entity Detected:Uncx, UNC homeobox ( MGI:108013)
Notes:The probe used in this study by Dunwoodie et al, 2002 [PMID:11923214] is described as that used used by Mansouri et al, 1997 [PMID:9286595] i.e. "a 700 bp fragment containing the homeobox". The actual sequence is unspecified.
Chemistry:RNA
Strand:antisense
Specimen
Organism:mouse
Strain:involves: 129P2/Ola * C57BL/6
Age:9.5 dpc
Theiler Stage:TS14
Mutations:Dll3tm1Rbe/Dll3+
Preparation:wholemount
Procedures
General Information
Authors:Dunwoodie SL; Clements M; Sparrow DB; Sa X; Conlon RA; Beddington RS 2002 [PMID:11923214] . Indexed by GXD, Spatially mapped by EMAGE
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ PMID:11923214] Dunwoodie SL, Clements M, Sparrow DB, Sa X, Conlon RA, Beddington RS 2002 Axial skeletal defects caused by mutation in the spondylocostal dysplasia/pudgy gene Dll3 are associated with disruption of the segmentation clock within the presomitic mesoderm. Development (129):1795-806
 [ doi:10.1002/(SICI)1097-0177(199709)210:1<53::AID-AJA6>3.0.CO;2-0] [ PMID:9286595] Mansouri A, Yokota Y, Wehr R, Copeland NG, Jenkins NA, Gruss P 1997 Paired-related murine homeobox gene expressed in the developing sclerotome, kidney, and nervous system. Dev Dyn (210):53-65
Links:MGI:2178636 same experiment
 MGI:2178443 allele description
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceMGI