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EMAGE:3893

Wnt1 wingless-related MMTV integration site 1 ( MGI:98953)
TS17 (37 Somite no.)
in situ hybridisation

Data Images
EMAGE:3893
Figure 3I. Copyright: Reprinted with permission from Elsevier from [doi:10.1016/S1567-133X(03)00087-5] Gene Expr Patterns 3: 397-405, Zhou XH; Brandau O; Feng K; Oohashi T; Ninomiya Y; Rauch U; Fassler R, The murine Ten-m/Odz genes show distinct but overlapping expression patterns during development and in adult brain. Copyright 2003.

Expression pattern clarity: two stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Notes:
Note: Mid/hindbrain junction (arrow), dorsal midline of the midbrain down to the spinal cord (arrow head, sp).
Expression Pattern Description
Spatial Annotation:
EMAGE:3893Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
3893_wholemount_strong_3D_1.wlz
3893_wholemount_moderate_3D_1.wlz
3893_wholemount_weak_3D_1.wlz
3893_wholemount_possible_3D_1.wlz
3893_wholemount_notDetected_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:3893_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: two stars
Text Annotation:
StructureLevelPatternNotes
hindbrain
detected detected
regionalExpression is at the midbrain/hindbrain junction and in the dorsal midline.
midbrain
detected detected
regionalExpression is at the midbrain/hindbrain junction and in the dorsal midline.
future spinal cord
detected detected
regionalExpression is in the dorsal midline.
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:MGI:2683021
Entity Detected:Wnt1, wingless-related MMTV integration site 1 ( MGI:98953)
Notes:The Wnt1 probe used in this study by Zhou et al., 2003 [PMID:12915301] is described as that originally described by McMahon et al., 1992 [PMID:1534034] . Editors note: McMahon et al. describe three Wnt1 in situ probes (Wnt13'a, Wnt13'b and Wnt15'). It is not specified which was used in this study by Zhou et al.
Chemistry:RNA
Strand:antisense
Label:digoxigenin
Specimen
Organism:mouse
Strain:C57BL/6
Age:37 Somite no.
Theiler Stage:TS17
Mutations:none (wild-type)
Preparation:wholemount
Procedures
Fixation:4% paraformaldehyde
General Information
Authors:Zhou XH; Brandau O; Feng K; Oohashi T; Ninomiya Y; Rauch U; Fassler R, 2003 [PMID:12915301] . Indexed by GXD, Spatially mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ doi:10.1016/0092-8674(92)90222-X] [ PMID:1534034] McMahon AP, Joyner AL, Bradley A, McMahon JA 1992 The midbrain-hindbrain phenotype of Wnt-1-/Wnt-1- mice results from stepwise deletion of engrailed-expressing cells by 9.5 days postcoitum. Cell (69):581-95
 [ doi:10.1016/0092-8674(92)90222-X] [ PMID:1534034] McMahon AP, Joyner AL, Bradley A, McMahon JA 1992 The midbrain-hindbrain phenotype of Wnt-1-/Wnt-1- mice results from stepwise deletion of engrailed-expressing cells by 9.5 days postcoitum. Cell (69):581-95
Links:MGI:2683022 same experiment
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceMGI