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EMAGE:3909

En2 engrailed 2 ( MGI:95390)
TS12 (8.5 dpc)
in situ hybridisation

Data Images
EMAGE:3909 EMAGE:3909
Fig 1C. Copyright: Reprinted with permission from Elsevier from [doi:10.1006/dbio.1996.0120] Dev Biol 175: 347-57, Avantaggiato V; Acampora D; Tuorto F; Simeone A, Retinoic acid induces stage-specific repatterning of the rostral central nervous system. Copyright 1996 Fig 1B'. Copyright: Reprinted with permission from Elsevier from [doi:10.1006/dbio.1996.0120] Dev Biol 175: 347-57, Avantaggiato V; Acampora D; Tuorto F; Simeone A, Retinoic acid induces stage-specific repatterning of the rostral central nervous system. Copyright 1996

Expression pattern clarity: three stars
Find spatially similar expression patterns: Find spatially similar patterns
Notes:
Image B' is a brightfield section at a roughly corresponding position to the darkfield image shown in image C. Image annotations: Filled arrowhead in C points to the position corresponding to the posterior border of Otx2; mb - midbrain; hb - hindbrain; fb - forebrain; fg - foregut.
Expression Pattern Description
Spatial Annotation:
EMAGE:3909EMAGE:3909Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
3D mappingspatial mapping

View mapped 3D expression image EMAGE genex expression entry
Download individual expression domains:
3909_voxel_strong_3D_1.wlz
3909_voxel_notDetected_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:3909_all_domains.zip
Find spatially similar expression patterns: EMAGE spatially similar patterns
Morphological match to the template: two stars
Text Annotation:
StructureLevelPatternNotes
future midbrain
detected detected
regionalEn-2 is expressed in the posterior midbrain.
future hindbrain
detected detected
regionalEn-2 is expressed in the rostral hindbrain.
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:MGI:1339318
Entity Detected:En2, engrailed 2 ( MGI:95390)
Notes:The En2 probe used in this study by Avantaggiato et al., 1996 [PMID:8626038] is described as a cDNA-derived fragment provided by Dr. Rosa Magda Alvarado-Mallart. No further information as to its identity is given.
Chemistry:RNA
Strand:antisense
Label:S35
Specimen
Organism:mouse
Age:8.5 dpc
Theiler Stage:TS12
Mutations:none (wild-type)
Preparation:section
Procedures
Staining procedure:autoradiography
General Information
Authors:Avantaggiato V; Acampora D; Tuorto F; Simeone A, 1996 [PMID:8626038] , Indexed by GXD, Spatially Mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ doi:10.1006/dbio.1996.0120] [ PMID:8626038] Avantaggiato V, Acampora D, Tuorto F, Simeone A 1996 Retinoic acid induces stage-specific repatterning of the rostral central nervous system. Dev Biol (175):347-57
Links:MGI:1339330 same experiment
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceMGI