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EMAGE:4000

Hoxa11 homeobox A11 ( MGI:96172)
TS15 (9.75 dpc)
in situ hybridisation

Data Images
EMAGE:4000 EMAGE:4000
Fig5D. Copyright: Reprinted with permission from Elsevier from [doi:10.1006/dbio.1993.1145] Dev Biol 157: 410-22, Haack H; Gruss P, The establishment of murine Hox-1 expression domains during patterning of the limb. Copyright 1993 Fig5A. Copyright: Reprinted with permission from Elsevier from [doi:10.1006/dbio.1993.1145] Dev Biol 157: 410-22, Haack H; Gruss P, The establishment of murine Hox-1 expression domains during patterning of the limb. Copyright 1993

Expression pattern clarity: two stars
Find spatially similar expression patterns: Find spatially similar patterns
Notes:
Image annotations: d - dorsal, v - ventral. Figure 5A is a brightfield image of an adjacent section to that shown in Figure 5D.
Expression Pattern Description
Spatial Annotation:
EMAGE:4000EMAGE:4000Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
3D mappingspatial mapping

View mapped 3D expression image EMAGE genex expression entry
Download individual expression domains:
4000_voxel_strong_3D_1.wlz
4000_voxel_notDetected_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:4000_all_domains.zip
Find spatially similar expression patterns: EMAGE spatially similar patterns
Morphological match to the template: two stars
Text Annotation:
StructureLevelPatternNotes
mesenchyme derived from somatopleure
detected detected
regionalExpression is also seen in a region adjacent to the somites. The authors call this somatopleural expression.
forelimb bud
detected detected
regionalExpression is restricted to the ventral, distal side of the limb. Expression in the posterior half is more extended.
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:MGI:1344039
Entity Detected:Hoxa11, homeobox A11 ( MGI:96172)
Notes:The Hoxa11 (Hox-1.9) probe template used in this study by Haack and Gruss, 1993 [PMID:8099045] is described as a "homeobox containing plasmid pbH1.9-158S-R (159-bp Hox-1.9 fragment)." Editors note: The actual probe sequence is not reported by the authors.
Chemistry:RNA
Strand:antisense
Label:S35
Specimen
Organism:mouse
Age:9.75 dpc
Theiler Stage:TS15
Mutations:none (wild-type)
Preparation:section
Procedures
Fixation:4% paraformaldehyde
Embedding:paraplast
Staining procedure:autoradiography
General Information
Authors:Haack H; Gruss P, 1993 [PMID:8099045] , Indexed by GXD, Spatially Mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ doi:10.1006/dbio.1993.1145] [ PMID:8099045] Haack H, Gruss P 1993 The establishment of murine Hox-1 expression domains during patterning of the limb. Dev Biol (157):410-22
Links:MGI:1344727 same experiment
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceMGI