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EMAGE:4042

Tubb3 tubulin, beta 3 class III ( MGI:107813)
TS17 (11 dpc)
immunohistochemistry

Data Images
EMAGE:4042 EMAGE:4042 EMAGE:4042
Figure 2D. Copyright: Reprinted with permission from Elsevier from [doi:10.1016/j.modgep.2004.12.002] Gene Expr Patterns 5: 517-23, Hirai S; Kawaguchi A; Suenaga J; Ono M; Cui de F; Ohno S, Expression of MUK/DLK/ZPK, an activator of the JNK pathway, in the nervous systems of the developing mouse embryo. Copyright 2005. Figure 2E. Copyright: Reprinted with permission from Elsevier from [doi:10.1016/j.modgep.2004.12.002] Gene Expr Patterns 5: 517-23, Hirai S; Kawaguchi A; Suenaga J; Ono M; Cui de F; Ohno S, Expression of MUK/DLK/ZPK, an activator of the JNK pathway, in the nervous systems of the developing mouse embryo. Copyright 2005. Figure 2F. Copyright: Reprinted with permission from Elsevier from [doi:10.1016/j.modgep.2004.12.002] Gene Expr Patterns 5: 517-23, Hirai S; Kawaguchi A; Suenaga J; Ono M; Cui de F; Ohno S, Expression of MUK/DLK/ZPK, an activator of the JNK pathway, in the nervous systems of the developing mouse embryo. Copyright 2005.

Expression pattern clarity: three stars
Find spatially similar expression patterns: Find spatially similar patterns
Notes:
Note: Sagittal sections. Arrows indicate neurons of brain and spinal cord. Abbreviations: tc, telencephalon; dc, diencephalon; mc, mesencephalon; IV, forth ventricle; sc, spinal cord; tg, trigeminal ganglion; fa, facio-acoustic ganglion; gp, glossopharyngeal ganglion; sv, superior ganglion of vagus nerve; iv, inferior ganglion of vagus nerve; drg, dorsal root ganglion; liv, liver primordium. Scale bar, 1 mm.
Expression Pattern Description
Spatial Annotation:
EMAGE:4042EMAGE:4042EMAGE:4042EMAGE:4042Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
3D mapping3D mapping3D mappingspatial mapping

View mapped 3D expression image EMAGE genex expression entry
Download individual expression domains:
4042_voxel_moderate_3D_1.wlz
4042_voxel_notDetected_3D_1.wlz
4042_voxel_strong_3D_1.wlz
4042_voxel_moderate_3D_2.wlz
4042_voxel_notDetected_3D_2.wlz
4042_voxel_strong_3D_2.wlz
4042_voxel_moderate_3D_3.wlz
4042_voxel_notDetected_3D_3.wlz
4042_voxel_strong_3D_3.wlz
(what is wlz format?)
Download all expression domains: EMAGE:4042_all_domains.zip
Find spatially similar expression patterns: EMAGE spatially similar patterns
Morphological match to the template: three stars
Text Annotation:
StructureLevelPatternNotes
central nervous system
detected detected
regionalExpression is in differentiated neurons.
Annotation Validation: EMAGE Editor
Detection Reagent
Type:antibody
Identifier:MGI:1860227
Entity Detected:Tubb3, tubulin, beta 3 class III ( MGI:107813)
Notes:The anti-Tubb3 antibody used in this study by Hirai et al., 2005 [PMID:15749080] was obtained from BabCO. This antibody recognizes a tubulin isoform is that exclusively present in neurons. It is frequently used because it is one of the earliest neuronal-specific markers.
Antibody Type:monoclonal
Raised In:mouse
Specimen
Organism:mouse
Age:11 dpc
Theiler Stage:TS17
Mutations:none (wild-type)
Preparation:section
Procedures
Fixation:4% paraformaldehyde
Embedding:paraffin
Secondary Antibody:anti-mouse IgG
Labelled with:alkaline phosphatase
Visualisation method:BMpurple
General Information
Authors:Hirai S; Kawaguchi A; Suenaga J; Ono M; Cui de F; Ohno S, 2005 [PMID:15749080] . Indexed by GXD, Spatially mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ doi:10.1016/j.modgep.2004.12.002] [ PMID:15749080] Hirai S, Kawaguchi A, Suenaga J, Ono M, Cui DF, Ohno S 2005 Expression of MUK/DLK/ZPK, an activator of the JNK pathway, in the nervous systems of the developing mouse embryo. Gene Expr Patterns (5):517-23
Links:MGI:3581155 same experiment
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceMGI