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EMAGE:4242

Gdf1 growth differentiation factor 1 ( MGI:95683)
TS15 (9.5 dpc)
in situ hybridisation

Data Images
EMAGE:4242
Fig4E. Copyright: Reprinted with permission from Elsevier from [doi:10.1006/dbio.2000.9926] Dev Biol 227: 495-509, Wall NA; Craig EJ; Labosky PA; Kessler DS, Mesendoderm induction and reversal of left-right pattern by mouse gdf1, a Vg1-related gene Copyright 2000

Expression pattern clarity: three stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Notes:
Image annotations: white arrowhead - ventral midbrain; white asterisk - lateral plate mesoderm.
Expression Pattern Description
Spatial Annotation:
EMAGE:4242Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
4242_wholemount_strong_3D_1.wlz
4242_wholemount_moderate_3D_1.wlz
4242_wholemount_possible_3D_1.wlz
4242_wholemount_notDetected_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:4242_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: three stars
Text Annotation:
StructureLevelPatternNotes
tail
detected detected
Expression is present in the tailbud.
mesenchyme
detected detected
regionalExpression is present in the ventrolateral mesoderm.
future spinal cord
detected detected
regionalExpression is present in the posterior spinal cord.
future midbrain
detected detected
regionalExpression is present at the cephalic flexure.
notochord
detected detected
regionalExpression is present in the posterior notochord.
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:MGI:3655649
Entity Detected:Gdf1, growth differentiation factor 1 ( MGI:95683)
Notes:The Gdf1 probe template used in this study by Wall et al., 2000 [PMID:11071769] is described as "a 772-bp SmaI fragment of Gdf1." Editors Note: SmaI digestion of the mouse Gdf1 mRNA RefSeq NM_008107.3 fails to identify a 772bp SmaI fragment. Insufficient information to define full probe sequence
Chemistry:RNA
Strand:antisense
Label:digoxigenin
Specimen
Organism:mouse
Age:9.5 dpc
Theiler Stage:TS15
Mutations:none (wild-type)
Preparation:wholemount
Procedures
General Information
Authors:Wall NA; Craig EJ; Labosky PA; Kessler DS, 2000 [PMID:11071769] , Indexed by GXD, Spatially Mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ doi:10.1006/dbio.2000.9926] [ PMID:11071769] Wall NA, Craig EJ, Labosky PA, Kessler DS 2000 Mesendoderm induction and reversal of left-right pattern by mouse Gdf1, a Vg1-related gene. Dev Biol (227):495-509
Links:MGI:3655650 same experiment
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceMGI