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EMAGE:4396

Lrrtm4 leucine rich repeat transmembrane neuronal 4 ( MGI:2389180)
TS18 (11.0 dpc)
in situ hybridisation

Data Images
EMAGE:4396 EMAGE:4396 EMAGE:4396 EMAGE:4396 EMAGE:4396
Fig4L. Copyright: Reprinted with permission from Elsevier from [doi:10.1016/j.modgep.2006.05.004] Gene Expr Patterns 7: 23-9, Haines BP; Rigby PW, Developmentally regulated expression of the LRRTM gene family during mid-gestation mouse embryogenesis. Copyright 2007 Fig4M. Copyright: Reprinted with permission from Elsevier from [doi:10.1016/j.modgep.2006.05.004] Gene Expr Patterns 7: 23-9, Haines BP; Rigby PW, Developmentally regulated expression of the LRRTM gene family during mid-gestation mouse embryogenesis. Copyright 2007 Fig4N. Copyright: Reprinted with permission from Elsevier from [doi:10.1016/j.modgep.2006.05.004] Gene Expr Patterns 7: 23-9, Haines BP; Rigby PW, Developmentally regulated expression of the LRRTM gene family during mid-gestation mouse embryogenesis. Copyright 2007 Fig4O. Copyright: Reprinted with permission from Elsevier from [doi:10.1016/j.modgep.2006.05.004] Gene Expr Patterns 7: 23-9, Haines BP; Rigby PW, Developmentally regulated expression of the LRRTM gene family during mid-gestation mouse embryogenesis. Copyright 2007 Fig4P. Copyright: Reprinted with permission from Elsevier from [doi:10.1016/j.modgep.2006.05.004] Gene Expr Patterns 7: 23-9, Haines BP; Rigby PW, Developmentally regulated expression of the LRRTM gene family during mid-gestation mouse embryogenesis. Copyright 2007

Expression pattern clarity: three stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Notes:
Image annotations: nt - neural tube; fp - floor plate; scl - sclerotome; dm - dermomyotome. Figs4M,N,O,P are sections taken the approximate regions shown by white lines in Fig4L.
Expression Pattern Description
Spatial Annotation:
EMAGE:4396Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
4396_wholemount_strong_3D_1.wlz
4396_wholemount_moderate_3D_1.wlz
4396_wholemount_notDetected_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:4396_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: three stars
Text Annotation:
StructureLevelPatternNotes
trunk somite
detected detected
regionalExpression is in stripes in the anterior mesoderm that are localized to a subset of cells in the developing sclerotome.
tail somite
detected detected
regionalExpression is in stripes in the anterior mesoderm that are localized to a subset of cells in the developing sclerotome.
hindlimb bud mesenchyme
weak weak
regionalExpression is in a wedge-shaped domain in the lateral mesenchyme of the hindlimb bud.
tail mesenchyme
detected detected
regionalExpression is in the ventral mesoderm posterior to the hind limbs.
neural tube
detected detected
tail neural tube
detected detected
forelimb bud mesenchyme
not detected not detected
homogeneous
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:MGI:3694249
Entity Detected:Lrrtm4, leucine rich repeat transmembrane neuronal 4 ( MGI:2389180)
Notes:The Lrrtm4 probe used in this study by Haines & Rigby, 2007 [PMID:16860615] is described as follows: "A LRRTM4 cDNA was obtained from IMAGE clone 5361681 digested with KpnI and BamHI. The fragment from 1 to 815 base pairs was cloned into KpnI and BamHI digested pBluescript II KS. An antisense probe was generated by digesting with BamHI and transcribing with T3 polymerase." Editors note: The complete insert sequence of IMAGE:5361681 is BC037216.1. This 2976nt sequence is cut by KpnI at nt1578 and BamHI at nt548 and nt947. Conflicting information, probe sequence unknown.
Chemistry:RNA
Strand:antisense
Label:digoxigenin
Specimen
Organism:mouse
Age:11.0 dpc
Theiler Stage:TS18
Mutations:none (wild-type)
Preparation:wholemount
Procedures
Staining procedure:alkaline phosphatase + NBT/Phos Red
General Information
Authors:Haines BP & Rigby PW, 2007 [PMID:16860615] , Indexed by GXD, Spatially Mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ doi:10.1016/j.modgep.2006.05.004] [ PMID:16860615] Haines BP, Rigby PW 2007 Developmentally regulated expression of the LRRTM gene family during mid-gestation mouse embryogenesis. Gene Expr Patterns (7):23-9
Links:MGI:3694269 same experiment
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceMGI