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EMAGE:452

Nkx2-1 NK2 homeobox 1 ( MGI:108067)
TS20 (12.5 dpc)
in situ hybridisation

Data Images
EMAGE:452
Figure 1F of Nery et al., 2001 [PMID:11171336] Copyright: This image is from Development and is displayed with the permission of The Company of Biologists Ltd. who owns the copyright.

Expression pattern clarity: three stars
Find spatially similar expression patterns: Find spatially similar patterns
Expression Pattern Description
Spatial Annotation:
EMAGE:452EMAGE:452Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
3D mapping3D context movie

View mapped 3D expression image EMAGE genex expression entry
Download individual expression domains:
452_voxel_strong_3D_1.wlz
452_voxel_possible_3D_1.wlz
452_voxel_notDetected_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:452_all_domains.zip
Find spatially similar expression patterns: EMAGE spatially similar patterns
Morphological match to the template: two stars
Text Annotation:
StructureLevelPatternNotes
telencephalon
detected detected
regionalExpression is detected in the ventral telencephalon.
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:MGI:1930280
Entity Detected:Nkx2-1, NK2 homeobox 1 ( MGI:108067)
Notes:The Titf1 (Nkx2.1) probe used in this study by Nery et al., 2001 [PMID:11171336] is indicated as that used by Shimamura et al., 1995 [PMID:8575293] which is of undefined sequence.
Chemistry:RNA
Strand:antisense
Label:digoxigenin
Specimen
Organism:mouse
Strain:Swiss Webster or CD1
Age:12.5 dpc
Theiler Stage:TS20
Mutations:none (wild-type)
Preparation:section
Procedures
Fixation:4% paraformaldehyde
Embedding:cryosection
General Information
Authors:Nery et al., 2001 [PMID:11171336] Indexed by GXD, Spatially mapped by EMAGE
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ PMID:11171336] Nery S, Wichterle H, Fishell G 2001 Sonic hedgehog contributes to oligodendrocyte specification in the mammalian forebrain. Development (128):527-40
 [ PMID:8575293] Shimamura K, Hartigan DJ, Martinez S, Puelles L, Rubenstein JL 1995 Longitudinal organization of the anterior neural plate and neural tube. Development (121):3923-33
Links:MGI:1930435 same experiment
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceMGI