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EMAGE:4592

Cdx2 caudal type homeobox 2 ( MGI:88361)
TS14 (9.5 dpc)
in situ hybridisation

Data Images
EMAGE:4592
Figure 4F. Copyright: This image is from Kanai-Azuma et al., Development 129:2367-2379 (2002), [PMID:11973269] and is displayed with the permission of The Company of Biologists Limited who owns the Copyright.

Expression pattern clarity: two stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Notes:
Note: red arrow indicates endoderm in the posterior embryo.
Expression Pattern Description
Spatial Annotation:
EMAGE:4592Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
4592_wholemount_moderate_3D_1.wlz
4592_wholemount_possible_3D_1.wlz
4592_wholemount_notDetected_3D_1.wlz
4592_wholemount_strong_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:4592_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: two stars
Text Annotation:
StructureLevelPatternNotes
gut
detected detected
Expression is present in the endoderm.
mesenchyme
detected detected
regionalExpressed in tail.
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:MGI:263093
Entity Detected:Cdx2, caudal type homeobox 2 ( MGI:88361)
Sequence:sense strand is shown

>MGI:263093
GCGGCCGCGGCGGCTGCTACGGCGAACTTGGACAGCGCTCAGTCCCCAGGGCCATCCTGGCCCACCGCGT
ACGGCGCCCCTCTCCGCGAGGACTGGAATGGCTACGCACCCGGGGGCGCTGCGGCAGCCAACGCGGTAGC
CCACGGTCTCAATGGTGGCTCCCCGGCCGCCGCTATGGGCTACAGCAGCCCCGCCGAATACCACGCGCAC
CATCACCCGCATCATCACCCGCACCATCCGGCCGCCTCGCCGTCCTGCGCCTCCGGCTTGCTGCAGACGC
TCAACCTCGGCCCCCCGGGGCCCGCAGCCACCGCCGCCGCCGAACAGCTGTCCCCCAGCGGCCAGCGGCG
AAACCTGTGCGAGTGGATGCGGAAGCCCGCGCAGCAGTCCCTAGGAAGCCAAGTGAAAACCAGGACAAAA
GACAAATACCGGGTGGTG
Notes:The Cdx2 probe used in this study by Kanai-Azuma et al., 2002 [PMID:11973269] is indicated as follows: "Beck et al, 1995 [PMID:8573715] (Accession Number, AI327188)". Editors note: Beck et al describe the generation and use in immunohistochemical studies of an anti-CDX2 antisera, however the alternative description given by Kanai-Azuma et al, AI327188, refers to a partial (3') sequence read from IMAGE:437757. It is presumed that the probe was transcribed from IMAGE:437757.
Chemistry:RNA
Strand:antisense
Specimen
Organism:mouse
Strain:involves: 129S1/Sv
Age:9.5 dpc
Theiler Stage:TS14
Mutations:Sox17tm1Ysk/Sox17+
Preparation:wholemount
Procedures
General Information
Authors:Kanai-Azuma M; Kanai Y; Gad JM; Tajima Y; Taya C; Kurohmaru M; Sanai Y; Yonekawa H; Yazaki K; Tam PP; Hayashi Y, 2002 [PMID:11973269] . Indexed by GXD, Spatially mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ PMID:11973269] Kanai-Azuma M, Kanai Y, Gad JM, Tajima Y, Taya C, Kurohmaru M, Sanai Y, Yonekawa H, Yazaki K, Tam PP, Hayashi Y 2002 Depletion of definitive gut endoderm in Sox17-null mutant mice. Development (129):2367-79
 [ doi:10.1002/aja.1002040302] [ PMID:8573715] Beck F, Erler T, Russell A, James R 1995 Expression of Cdx-2 in the mouse embryo and placenta: possible role in patterning of the extra-embryonic membranes. Dev Dyn (204):219-27
Links:MGI:2180035 same experiment
 MGI:2179440 allele description
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceMGI