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EMAGE:472

Bmp4 bone morphogenetic protein 4 ( MGI:88180)
TS19 (11.5 dpc)
in situ hybridisation

Data Images
EMAGE:472
Figure 7M of Wang et al., 2001 [PMID:11748138] . Copyright: This image is from Development and is displayed with permission of The Company of Biologists Ltd. who owns the copyright.

Expression pattern clarity: two stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Notes:
Arrows indicate the postion of the developing sensory patches in the otic vesicle.
Expression Pattern Description
Spatial Annotation:
EMAGE:472Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
472_wholemount_strong_3D_1.wlz
472_wholemount_moderate_3D_1.wlz
472_wholemount_notDetected_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:472_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: two stars
Text Annotation:
StructureLevelPatternNotes
inner ear
detected detected
regionalExpression is present in the future cristae (two clusters of cells at the anterior and posterior edges of the otic epithelium).
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:MGI:2155100
Entity Detected:Bmp4, bone morphogenetic protein 4 ( MGI:88180)
Notes:The probe used in this study by Wang et al., 2001 [PMID:11748138] is described as a "1.2 kb Bmp4 " fragment.
Chemistry:RNA
Strand:antisense
Label:digoxigenin
Specimen
Organism:mouse
Age:11.5 dpc
Theiler Stage:TS19
Mutations:none (wild-type)
Preparation:wholemount
Procedures
General Information
Authors:Wang et al., 2001 [PMID:11748138] . Indexed by GXD, Spatially mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ PMID:11748138] Wang W, Chan EK, Baron S, Van de Water T, Lufkin T 2001 Hmx2 homeobox gene control of murine vestibular morphogenesis. Development (128):5017-29
Links:MGI:2155130 same experiment
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceMGI