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EMAGE:49

Otx2 orthodenticle homolog 2 (Drosophila) ( MGI:97451)
TS10
in situ hybridisation

Data Images
EMAGE:49
Figure 2B (2nd embryo from left in that figure), Ang et al., 1994 [PMID:7607086] . Copyright: This image is from Development and is displayed with the permission of the Company of Biologists Ltd. who owns the copyright.

Expression pattern clarity: three stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Notes:
Embryo described by Ang et al., 1994 [PMID:7607086] as being within the mid- to late-streak stages
Expression Pattern Description
Spatial Annotation:
EMAGE:49Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
49_wholemount_strong_3D_1.wlz
49_wholemount_weak_3D_1.wlz
49_wholemount_notDetected_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:49_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: three stars
Text Annotation:
StructureLevelPatternNotes
embryo
detected detected
regionalBetween the early- and late-streak stages, Otx2 expression becomes progressively restricted to the anterior half of the embryo.
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:MGI:23226
Entity Detected:Otx2, orthodenticle homolog 2 (Drosophila) ( MGI:97451)
Notes:The Otx2 probe used in this study by Ang et al., 1994 [PMID:7607086] is called pOtd9 by the authors and is depicted in Figure 1B of that paper. The figure shows the region covered by probe. The probe includes the homeodomain coding region.
Chemistry:RNA
Strand:antisense
Label:digoxigenin
Specimen
Organism:mouse
Strain:CD1
Theiler Stage:TS10
Mutations:none (wild-type)
Preparation:wholemount
Procedures
Staining procedure:undefined
General Information
Authors:Ang et al., 1994 [PMID:7607086] Indexed by GXD, Spatially mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ PMID:7607086] Ang SL, Conlon RA, Jin O, Rossant J 1994 Positive and negative signals from mesoderm regulate the expression of mouse Otx2 in ectoderm explants. Development (120):2979-89
Links:MGI:1275040 same experiment
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceMGI