EMAGE mouse gene expression spatial database

EMAGE:5239

Skor2 SKI family transcriptional corepressor 2 ( MGI:3645984)
TS19 (11 dpc)
in situ hybridisation

Data Images


Fig2C. from [doi:10.1038/labinvest.3700344] Lab Invest 2005 85(11): 1330-41, Arndt S; Poser I; Schubert T; Moser M; Bosserhoff AK, Cloning and functional characterization of a new Ski homolog, Fussel-18, specifically expressed in neuronal tissues. 2005 [PMID:16200078] © Nature Publishing Group. Reproduced with permission from Lab Invest.

Expression pattern clarity:
Find spatially similar wholemount expression patterns:

Notes:

Image annotation: the arrowhead points to expression in dorsal root ganglia.

Expression Pattern Description

Spatial Annotation:

Annotation colour key:

wholemount mapping

Download individual expression domains:

Download all expression domains:

Find spatially similar wholemount expression patterns:

Morphological match to the template:

Text Annotation:

Structure

Level

Pattern

Notes

hindbrain

detected

regional

Fussel-18 is already expressed at E11 in a thin stripe anterior of the fourth ventricle, which will form the future cerebellum.

dorsal root ganglion

strong

strong staining is also observed in the dorsal root ganglia that are located lateral to the neural tube and belong to the peripheral nervous system.

Annotation Validation:

EMAGE Editor

Detection Reagent

Type:	in situ hybridisation probe
Identifier:	MGI:3665316
Entity Detected:	Skor2, SKI family transcriptional corepressor 2 ( MGI:3645984)
Sequence:	sense strand is shown >MGI:3665316 CCAACCTCAAACCCAACCAGGTGGGCCAGGTGATCCTCTACGGCATTCCCATCGTGTCGTTGGTGATCGA CGGGCAAGAGCGCCTGTGCCTGGCGCAGATCTCCAACACTCTGCTCAAGAACTTCAGCTACAACGAGATC CACAACCGTCGCGTGGCACTGGGCATCACGTGTGTGCAGTGCACGCCGGTGCAACTGGAGATCCTGCGGC GTGCCGGGGCCATGCCCATCTCATCGCGCCGCTGCGGCATGATCACCAAACGCGAGGCCGAGCGTCTGTG CAAGTCGTTCCTGGGCGAAAACAGGCCGCCCAAGCTGCCAGACAATTTCGCCTTCGACGTGTCACACGAG TGCGCCTGGGGCTGCCGCGGCAGCTTCATTCCCGCGCGCTACAACAGCTCGCGCGCCAAGTGCATCAAAT GCAGCTACTGCAACATGTACTTCTCGCCCAACAAGTTCATTTTCCACTCCCACCGCACGCCCGACGCCAA GTACACTCAGCCAGACGCAGCCAACTTCAACTC
	nt 101 - nt 623 of AY669508.1
Notes:	The EG664805 (fussel-18) probe used in this study by Arndt et al., 2005 [PMID:16200078] is described as follows: "a 522-bp fragment obtained from the human fussel 18 cDNA were amplified by PCR using following primers fussel18 fw 101: 5'cca acc tca aac cca acc ag3' and fussel18 rev 623: 5'gag ttg aag ttg gct gcg tc3' and subcloned into pCRII-TOPO. Owing to the high homology between the human and mouse fussel 18 cDNAs, this probe was also used for hybridizations of murine tissues."
Chemistry:	RNA
Strand:	antisense

Specimen

Procedures

General Information

Authors:	Arndt S; Poser I; Schubert T; Moser M; Bosserhoff AK, 2005 [PMID:16200078] , Indexed by GXD, Spatially mapped by EMAGE
Submitted by:	EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:	non-screen
References:	[ doi:10.1038/labinvest.3700344] [ PMID:16200078] Arndt S, Poser I, Schubert T, Moser M, Bosserhoff AK 2005 Cloning and functional characterization of a new Ski homolog, Fussel-18, specifically expressed in neuronal tissues. Lab Invest (85):1330-41
Links:	MGI:3665317 same experiment
	MGI:3665319 primer sequences
	Ensembl same gene
	Allen Brain Atlas same gene
	BioGPS same gene
	International Mouse Knockout Project Status same gene
	GEISHA Chicken ISH Database same gene
	EMBL-EBI Gene Expression Atlas same gene
	BrainStars same gene
	ViBrism same gene
Data Source