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EMAGE:540

Tlx2 T-cell leukemia, homeobox 2 ( MGI:1350935)
TS12 (8.5 dpc)
in situ hybridisation

Data Images
EMAGE:540
Fig 1G Tang et al, 1998 [PMID:9550720] . Copyright: This image is from Development and is displayed with the permission of the Company of Biologists Ltd. who owns the copyright.

Expression pattern clarity: no stars
Notes:
White arrow points to the primitive streak, Black arrowhead points to the node.
Expression Pattern Description
Text Annotation:
StructureLevelPatternNotes
primitive streak
detected detected
regionalTlx-2 was prominently expressed in the posterior end of the primitive streak and extended laterally on either side.
embryo
weak weak
regionalRelatively low expression in the node was observed at E8.5
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:MGI:1276508
Entity Detected:Tlx2, T-cell leukemia, homeobox 2 ( MGI:1350935)
Notes:Two Tlx2 probes were used in this study by Tang et al, 1998 [PMID:9550720] , both of which are of unspecified sequence and both of which "yielded the same expression pattern, whereas the corresponding sense probes did not produce specific signals".
Chemistry:RNA
Strand:antisense
Label:digoxigenin
Specimen
Organism:mouse
Strain:CD1
Age:8.5 dpc
Theiler Stage:TS12
Mutations:none (wild-type)
Preparation:wholemount
Procedures
General Information
Authors:Tang et al, 1998 [PMID:9550720] Indexed by GXD.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ PMID:9550720] Tang SJ, Hoodless PA, Lu Z, Breitman ML, McInnes RR, Wrana JL, Buchwald M 1998 The Tlx-2 homeobox gene is a downstream target of BMP signalling and is required for mouse mesoderm development. Development (125):1877-87
Links:MGI:1316852 same experiment
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceMGI