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EMAGE:549

Msx1 homeobox, msh-like 1 ( MGI:97168)
TS17 (35 Somite no.)
in situ hybridisation

Data Images
EMAGE:549 EMAGE:549 EMAGE:549
Fig 4B (Msx1, upper) Hadrys et al, 1998 [PMID:9389661] . Copyright: This image is from Development and is displayed with the permission of the Company of Biologists Ltd who owns the copyright. Fig 4B (Msx1, lower) Hadrys et al, 1998 [PMID:9389661] . Copyright: This image is from Development and is displayed with the permission of the Company of Biologists Ltd who owns the copyright. Fig 4B Hadrys et al, 1998 [PMID:9389661] . Copyright: This image is from Development and is displayed with the permission of the Company of Biologists Ltd who owns the copyright.

Expression pattern clarity: two stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Find spatially similar expression patterns: Find spatially similar patterns
Notes:
The wholemount stained embryo in Image 1 was vibratome sectioned to produce Image 2. The approximate plane of section is indicated in the cartoon in Image 3.
Expression Pattern Description
Spatial Annotation:
EMAGE:549EMAGE:549EMAGE:549Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
3D mappingspatial mappingwholemount mapping

View mapped 3D expression image EMAGE genex expression entry
Download individual expression domains:
549_wholemount_strong_3D_2.wlz
549_wholemount_notDetected_3D_2.wlz
549_voxel_strong_3D_1.wlz
549_voxel_possible_3D_1.wlz
549_voxel_notDetected_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:549_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Find spatially similar expression patterns: EMAGE spatially similar patterns
Morphological match to the template: one star
Text Annotation:
StructureLevelPatternNotes
otocyst
detected detected
regionalMsx-1 expression overlaps the expression of Nkx5-1 in the lateral wall of the otocyst
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:MGI:1197233
Entity Detected:Msx1, homeobox, msh-like 1 ( MGI:97168)
Sequence:sense strand is shown

>MGI:1197233
AGATCTGGTTCCAGAACCGTCGCGCTAAGGCCAAGAGACTGCAGGAGGCGGAGCTGGAGAAGCTGAAGAT
GGCCGCGAAACCCATGTTGCCGCCTGCTGCCTTCGGCCTCTCTTTTCCTCTTGGCGGTCCTGCAGCTGCG
GGCGCCTCACTCTACAGTGCCTCTGGCCCTTTCCAGCGCGCCGCGCTGCCTGTAGCGCCCGTGGGACTCT
ACACCGCCCATGTAGGCTACAGCATGTACCACCTGACTTAGGTGGGTCCAGAGTCACCTCCCTGTGGTGC
CATCCCCTCCCCAGCCACCTCTTTGAGCAGAGCAGCGGGAGTCCTTCCTAGGAAGCTCTGCTGCCCTATA
CCACCTGGTCCCTTCTCTTAAACCCCTTGCTACACACTTCCTCCTGGTTGTCGCTTCCTAAACCTTCCTC
ATCTGACCCCTTCTGGGAAGAAAAAGAATTGGTCGGAAGATGTTCAGGTTTTTCGAGTTTTTTCTAGATT
TACATGCGCAAGTTATAAAATGTGGAAACTAAGGATGCAGAGGCCAAGAGATTTATCCGTGGTCCCCAGC
AGAATTAGAGGCTGAAGGAGACCAGAGGCCAAAAGGACTAGAGGCCATGAGACTCCATCAGCTGCTTCCG
GTCCTGAAACCAGGCAGGACTTGCACAGAGAAATTGCTAAGCTAATCGGTGCTCCAAGAGATGAGCCCAG
CCCTATAGAAAGCAAGAGCCCAGCTCCTTCCACTGTCAAACTCTAAGCGCTTTGGCAGCAAAGCATTGCT
CTGAGGGGGCAGGGCGCATGCTGCTGCTTCACCAAGGTAGGTTAAAGAGACTTTCCCAGGACCAGAAAAA
AAGAAGTAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAACAAATCTGTTCTATTAACAGTACATTTTCGTG
GCTCTCAAGCATCCCTTTTGAAGGGACTGGTGTGTACTATGTAATATACTGTATATTTGAAATTTTATTA
TCATTTATATTATAGCTATATTTGTTAAATAAATTAATTTTAAGCTACAN
nt 773 - nt 1802 of X59251.1
Notes:The Msx1 probe used in this study by Hadrys et al, 1998 [PMID:9389661] is described as "a 1.2 kb cDNA fragment (Hill et al., 1989 [PMID:2565278] ) ". The 1.2 kb probe used by Hill is shown as extending from the BglII site to the 3'end of the cDNA in Fig6 of that paper and called 'Probe1'.
Chemistry:RNA
Strand:antisense
Specimen
Organism:mouse
Strain:C57BL/6
Age:35 Somite no.
Theiler Stage:TS17
Mutations:none (wild-type)
Preparation:sectioned wholemount
Procedures
General Information
Authors:Hadrys et al, 1998 [PMID:9389661] Indexed by GXD, Spatially mapped by EMAGE
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ PMID:9389661] Hadrys T, Braun T, Rinkwitz-Brandt S, Arnold HH, Bober E 1998 Nkx5-1 controls semicircular canal formation in the mouse inner ear. Development (125):33-9
 [ doi:10.1101/gad.3.1.26] [ PMID:2565278] Hill RE, Jones PF, Rees AR, Sime CM, Justice MJ, Copeland NG, Jenkins NA, Graham E, Davidson DR 1989 A new family of mouse homeo box-containing genes: molecular structure, chromosomal location, and developmental expression of Hox-7.1. Genes Dev (3):26-37
Links:MGI:1303356 same experiment
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceMGI