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EMAGE:559

Wnt7a wingless-related MMTV integration site 7A ( MGI:98961)
TS18 (11.0 dpc)
in situ hybridisation

Data Images
EMAGE:559
Figure 4C of Hanks et al., 1998 [PMID:9778510] Copyright: This image is from Development and is displayed with the permission of The Company of Biologists Ltd. who owns the copyright.

Expression pattern clarity: three stars
Find spatially similar expression patterns: Find spatially similar patterns
Notes:
Dorsal is at the top of the image, ventral is bottom (as defined in Fig 4A of Hanks et al., 1998 [PMID:9778510] ).
Expression Pattern Description
Spatial Annotation:
EMAGE:559EMAGE:559Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
3D mapping3D context movie

View mapped 3D expression image EMAGE genex expression entry
Download individual expression domains:
559_voxel_strong_3D_1.wlz
559_voxel_notDetected_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:559_all_domains.zip
Find spatially similar expression patterns: EMAGE spatially similar patterns
Morphological match to the template: one star
Text Annotation:
StructureLevelPatternNotes
limb
detected detected
regionalExpression is restricted to dorsal surface of limb.
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:MGI:9297
Entity Detected:Wnt7a, wingless-related MMTV integration site 7A ( MGI:98961)
Notes:The probe used in this study by Hanks et al., 1998 [PMID:9778510] is indicated as being that used by Loomis et al., 1996 [PMID:8684466] who in turn reference Parr & McMahon, 1995 [PMID:7885472] who in turn reference Parr et al., 1993 [PMID:8275860] who describe the probe as "400bp SmaI-EcoRI (coding and 3' untranslated)."
Chemistry:RNA
Strand:antisense
Label:S35
Specimen
Organism:mouse
Age:11.0 dpc
Theiler Stage:TS18
Mutations:none (wild-type)
Preparation:section
Procedures
Staining procedure:autoradiography
General Information
Authors:Hanks et al., 1998 [PMID:9778510] Indexed by GXD, Spatially mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ PMID:9778510] Hanks MC, Loomis CA, Harris E, Tong CX, Anson-Cartwright L, Auerbach A, Joyner A 1998 Drosophila engrailed can substitute for mouse Engrailed1 function in mid-hindbrain, but not limb development. Development (125):4521-30
 [ doi:10.1038/382360a0] [ PMID:8684466] Loomis CA, Harris E, Michaud J, Wurst W, Hanks M, Joyner AL 1996 The mouse Engrailed-1 gene and ventral limb patterning. Nature (382):360-3
 [ doi:10.1038/374350a0] [ PMID:7885472] Parr BA, McMahon AP 1995 Dorsalizing signal Wnt-7a required for normal polarity of D-V and A-P axes of mouse limb. Nature (374):350-3
 [ PMID:8275860] Parr BA, Shea MJ, Vassileva G, McMahon AP 1993 Mouse Wnt genes exhibit discrete domains of expression in the early embryonic CNS and limb buds. Development (119):247-61
Links:MGI:1303360 same experiment
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceMGI