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EMAGE:644

Pax2 paired box gene 2 ( MGI:97486)
TS15 (9.0 dpc)
in situ hybridisation

Data Images
EMAGE:644
Fig 5E, Filosa et al, 1997 [PMID:9226455] . Copyright: This image is from Development and is displayed with the permission of the Company of Biologists Ltd. who owns the copyright.

Expression pattern clarity: two stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Notes:
Arrowhead points to mid-hindbrain junction.
Expression Pattern Description
Spatial Annotation:
EMAGE:644Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
644_wholemount_strong_3D_1.wlz
644_wholemount_moderate_3D_1.wlz
644_wholemount_possible_3D_1.wlz
644_wholemount_notDetected_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:644_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: three stars
Text Annotation:
StructureLevelPatternNotes
optic vesicle
detected detected
future brain
detected detected
regionalExpression is detected at the mid-hindbrain junction
inner ear
detected detected
regionalExpression is detected in the otic vesicles
trunk mesenchyme
detected detected
regionalExpression is detected in the lateral mesoderm
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:MGI:21330
Entity Detected:Pax2, paired box gene 2 ( MGI:97486)
Notes:The probe used in this study by Filosa et al, 1997 [PMID:9226455] is described as that used by Nornes et al, 1990 [PMID:1977575] ie. "a unique Pax2 cDNA fragment downstream from the paired box sequence to prevent potential cross hybridization with other paired box containing genes (Dressler et al, 1990 [PMID:1977574] )". Dressler describe the probe as a "527 bp BamHI-EcoRI fragment from clone c31A". Figs 1 and 2 in Dressler et al., 1990 contain ambiguities in nucleotide numbering.
Chemistry:RNA
Strand:antisense
Specimen
Organism:mouse
Strain:(129/Sv x C57BL/6) x (129/Sv x CD1)F1
Age:9.0 dpc
Theiler Stage:TS15
Mutations:none (wild-type)
Preparation:wholemount
Procedures
General Information
Authors:Filosa et al, 1997 [PMID:9226455] Indexed by GXD, Spatially mapped by EMAGE
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ PMID:9226455] Filosa S, Rivera-Perez JA, Gomez AP, Gansmuller A, Sasaki H, Behringer RR, Ang SL 1997 Goosecoid and HNF-3beta genetically interact to regulate neural tube patterning during mouse embryogenesis. Development (124):2843-54
 [ PMID:1977575] Nornes HO, Dressler GR, Knapik EW, Deutsch U, Gruss P 1990 Spatially and temporally restricted expression of Pax2 during murine neurogenesis. Development (109):797-809
 [ PMID:1977574] Dressler GR, Deutsch U, Chowdhury K, Nornes HO, Gruss P 1990 Pax2, a new murine paired-box-containing gene and its expression in the developing excretory system. Development (109):787-95
Links:MGI:1338531 same experiment
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceMGI