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EMAGE:691

Lhx6 LIM homeobox protein 6 ( MGI:1306803)
TS20 (12.5 dpc)
in situ hybridisation

Data Images
EMAGE:691
Fig 5p Corbin et al, 2003 [PMID:12930780] . Copyright: This image is from Development and is displayed with the permission of the Company of Biologists Ltd who owns the copyright.

Expression pattern clarity: three stars
Find spatially similar expression patterns: Find spatially similar patterns
Expression Pattern Description
Spatial Annotation:
EMAGE:691EMAGE:691Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
3D mapping3D context movie

View mapped 3D expression image EMAGE genex expression entry
Download individual expression domains:
691_voxel_strong_3D_1.wlz
691_voxel_notDetected_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:691_all_domains.zip
Find spatially similar expression patterns: EMAGE spatially similar patterns
Morphological match to the template: three stars
Text Annotation:
StructureLevelPatternNotes
telencephalon
detected detected
regional
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:MGI:2676163
Entity Detected:Lhx6, LIM homeobox protein 6 ( MGI:1306803)
Notes:The probe used in this study by Corbin et al, 2003 [PMID:12930780] is described as that used by Grigoriou et al, 1998 [PMID:9570771] . Grigoriou describe the probe as a "1.5 kb BamHI-EcoRI fragment of the 3'UTR". A restriction map of a ~6kb Lhx6 cDNA is shown in Fig1A therein whereas elsewhere in the legend for Fig1 the authors mention depositing a Lhx6 sequence in EMBL (AJ000337) which is only 1734nt in length. Ambiguous information, probe ends undefined.
Chemistry:RNA
Strand:antisense
Label:digoxigenin
Specimen
Organism:mouse
Age:12.5 dpc
Theiler Stage:TS20
Mutations:none (wild-type)
Preparation:section
Procedures
Fixation:4% paraformaldehyde
Embedding:cryosection
General Information
Authors:Corbin et al, 2003 [PMID:12930780] Indexed by GXD, Spatially mapped by EMAGE
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ doi:10.1242/dev.00717] [ PMID:12930780] Corbin JG, Rutlin M, Gaiano N, Fishell G 2003 Combinatorial function of the homeodomain proteins Nkx2.1 and Gsh2 in ventral telencephalic patterning. Development (130):4895-906
 [ PMID:9570771] Grigoriou M, Tucker AS, Sharpe PT, Pachnis V 1998 Expression and regulation of Lhx6 and Lhx7, a novel subfamily of LIM homeodomain encoding genes, suggests a role in mammalian head development. Development (125):2063-74
Links:MGI:2676245 same experiment
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceMGI