Quicksearch Help

(Click the icon to keep this page displayed.)

EMAGE:693

Nrg1 neuregulin 1 ( MGI:96083)
TS16 (10.0 dpc)
in situ hybridisation

Data Images
EMAGE:693
Figure 3E of Meyer et al., 1997 [PMID:9342050] Copyright: This image is from Development and is displayed with the permission of The Company of Biologists Ltd. who owns the copyright.

Expression pattern clarity: two stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Notes:
Image annotations: t - trigeminal; ge - geniculate; gl - glossopharyngeal; va - vagal ganglia; dc - dorsal spinal cord; drg - dorsal root ganglia; mn - motorneurons located in the ventral column of the spinal cord.
Expression Pattern Description
Spatial Annotation:
EMAGE:693Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
693_wholemount_strong_3D_1.wlz
693_wholemount_moderate_3D_1.wlz
693_wholemount_notDetected_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:693_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: three stars
Text Annotation:
StructureLevelPatternNotes
cranial ganglion
detected detected
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:MGI:2155222
Entity Detected:Nrg1, neuregulin 1 ( MGI:96083)
Notes:The pan-neuregulin (Nrg1) probe used in this study by Meyer et al., 1997 [PMID:9342050] was described as "corresponding to mouse cDNA encoding coding segments 3-7 and 11 (nucleotides 391-1458 in the reported rat NDF cDNA sequence (Wen et al., 1992 [PMID:1349853] )."
Chemistry:RNA
Strand:antisense
Label:digoxigenin
Specimen
Organism:mouse
Age:10.0 dpc
Theiler Stage:TS16
Mutations:none (wild-type)
Preparation:wholemount
Procedures
General Information
Authors:Meyer et al., 1997 [PMID:9342050] Indexed by GXD, Spatially Mapped by EMAGE
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ PMID:9342050] Meyer D, Yamaai T, Garratt A, Riethmacher-Sonnenberg E, Kane D, Theill LE, Birchmeier C 1997 Isoform-specific expression and function of neuregulin. Development (124):3575-86
 [ doi:10.1016/0092-8674(92)90456-M] [ PMID:1349853] Wen D, Peles E, Cupples R, Suggs SV, Bacus SS, Luo Y, Trail G, Hu S, Silbiger SM, Levy RB 1992 Neu differentiation factor: a transmembrane glycoprotein containing an EGF domain and an immunoglobulin homology unit. Cell (69):559-72
Links:MGI:2155230 same experiment
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceMGI